实用临床医药杂志2012，Vol.16Issue(11)：121-122,2.
COX-2在非小细胞肺癌中的表达及意义
Expression and significance of COX - 2 in non- small cell lung cancer
左一俊 1蔡雷鸣 1关乃福1
作者信息
- 1. 南京医科大学附属常州第二人民医院呼吸科,江苏常州,213003
- 折叠
摘要
Abstract
Objective To study the expression and significance of COX - 2 in non - small cell lung cancer( NSCLC). Methods The expression of protein COX - 2 was detected by immuno-histoehemistry technique in 88 NSCLC tissues and 23 normal lung cancer tissues. Results The expression of protein COX - 2 in NSCLC was significantly higher than that in normal cancer tissues (P<0.01). The expression of protein COX-2 was correlated with the clinical staging and histo-logical type, but was not correlated with the age, sex and transferred lymph node of the patients. Compared with other NSCLC, the expression of protein COX - 2 was obviously increased in adeno-carcinomas cell carcinomas. Conclusion The expression of protein COX -2 is up - regulated in NSCLC, especially in adenocarcinomas cell carcinomas. The expression of protein COX - 2 could be valuable indicators for predicting the prognosis of NSCLC.关键词
非小细胞肺癌/免疫组织化学/环氧化酶-2Key words
non-small cell lung cancer/ immunohistochemistry/ COX-2
分类
医药卫生引用本文复制引用
左一俊,蔡雷鸣,关乃福..COX-2在非小细胞肺癌中的表达及意义[J].实用临床医药杂志,2012,16(11):121-122,2.
