常州大学学报（自然科学版）2012，Vol.24Issue(1)：21-23,3.
噻唑-4-甲酸的合成
Synthesis of Thiazole-4-Carboxylic Acid
邱滔 1吴增辉 1吕新宇1
作者信息
- 1. 常州大学设计研究院,江苏常州 213164
- 折叠
摘要
Abstract
Methyl thiazolidine-4 - carboxylate was synthesized from L-Cysteine hydrochloride and formaldehyde by condensation and esterification. Methyl thiazole-4 -carboxylate was synthesized by oxidation reaction. Thiazole-4 -carboxylic acid was achieved from hydrolysis reaction. The mole ratio of methyl thiazole-4 - carboxylate to MnO2 was 1 : 23, the activation temperature of MnO2 was 300℃ , reaction for 48h at 80℃. The yield of oxidation reaction was 80. 8%.关键词
噻唑-4-甲酸/氧化反应/合成Key words
Thiazole-4 -carboxylic acid/ oxidation reaction/ synthetize分类
化学化工引用本文复制引用
邱滔,吴增辉,吕新宇..噻唑-4-甲酸的合成[J].常州大学学报（自然科学版）,2012,24(1):21-23,3.
