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半枝莲多糖的纯化及抗肿瘤作用的体内实验研究

杨姗姗 吴大军 张秀娟

江西农业大学学报2012,Vol.34Issue(2):392-396,5.
江西农业大学学报2012,Vol.34Issue(2):392-396,5.

半枝莲多糖的纯化及抗肿瘤作用的体内实验研究

Experimental Study on Anti-tumor Effects of Scutellaria barbata D.Don Polyaccharides in Vivo

杨姗姗 1吴大军 1张秀娟2

作者信息

  • 1. 淮安信息职业技术学院,江苏淮安223003
  • 2. 哈尔滨商业大学生命科学与环境科学研究中心生物安全评价研究所,国家教育部抗肿瘤天然药物工程研究中心,黑龙江哈尔滨150076
  • 折叠

摘要

Abstract

Objective: To study the purifying method for Scutellaria barbata D. Don polyaccharides ( SPS ) and its anti-tumor effect of SPS in entrails. Methods: Using Sevag and Phenol - sulfuric acid method the content of polysaccharide was determined,the anti - tumor effect of SPS and the spleen index and the thymus index were observed by tumor transplant experiment on animal. Results;SPS can inhibite the growth of SI80 and the effect on middle dose group was the best; the spleen index was affected remarkably in every group and the thymus index was inhibited by big dose (200 mg/kg). Conclusion: The content of polysaccharide purified with Sevay method and the polysaccharide content in crude polysaccharide were significantly different; the method is practical; SPS has anti - tumor effect and can improve immunity.

关键词

半枝莲/多糖纯化/抗肿瘤

Key words

Scutellaria barbata D. Don polyaccharides/ polyaccharides purification/ antitumor

分类

农业科技

引用本文复制引用

杨姗姗,吴大军,张秀娟..半枝莲多糖的纯化及抗肿瘤作用的体内实验研究[J].江西农业大学学报,2012,34(2):392-396,5.

基金项目

黑龙江省自然科学基金资助项目(D201043) (D201043)

江西农业大学学报

OA北大核心CSCDCSTPCD

1000-2286

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