江西农业大学学报2012,Vol.34Issue(2):392-396,5.
半枝莲多糖的纯化及抗肿瘤作用的体内实验研究
Experimental Study on Anti-tumor Effects of Scutellaria barbata D.Don Polyaccharides in Vivo
摘要
Abstract
Objective: To study the purifying method for Scutellaria barbata D. Don polyaccharides ( SPS ) and its anti-tumor effect of SPS in entrails. Methods: Using Sevag and Phenol - sulfuric acid method the content of polysaccharide was determined,the anti - tumor effect of SPS and the spleen index and the thymus index were observed by tumor transplant experiment on animal. Results;SPS can inhibite the growth of SI80 and the effect on middle dose group was the best; the spleen index was affected remarkably in every group and the thymus index was inhibited by big dose (200 mg/kg). Conclusion: The content of polysaccharide purified with Sevay method and the polysaccharide content in crude polysaccharide were significantly different; the method is practical; SPS has anti - tumor effect and can improve immunity.关键词
半枝莲/多糖纯化/抗肿瘤Key words
Scutellaria barbata D. Don polyaccharides/ polyaccharides purification/ antitumor分类
农业科技引用本文复制引用
杨姗姗,吴大军,张秀娟..半枝莲多糖的纯化及抗肿瘤作用的体内实验研究[J].江西农业大学学报,2012,34(2):392-396,5.基金项目
黑龙江省自然科学基金资助项目(D201043) (D201043)