临床肝胆病杂志2012,Vol.28Issue(7):545-547,3.
肝穿刺活组织病理检查在肝病诊治中的意义
Clinical significance of liver biopsy in diagnosis and treatment of liver disease
沈美蓉 1李仲平 1丁晓红 1储峰 1胡德昌2
作者信息
- 1. 上海市浦东新区南华医院,上海201300
- 2. 上海市中山医院,上海200032
- 折叠
摘要
Abstract
Objective To assess the clinical significance of liver biopsy for diagnosis and treatment of liver disease. Methods Patients with obscure liver disease who underwent liver biopsy under B - ultrasound guidance at our hospital between 2007 and 2011 were retrospectively analyzed. Results Sixteen cases with obscure liver disease were diagnosed after liver biopsy. Among them, four cases (25.0% ) were diagnosed as drug induced hepatitis, four (25.0% ) as fatty liver disease, two (12.5% ) as autoimmune hepatitis, two (12.5% ) as hepatitis B virus infection, one (6.3% ) as acute viral cholestatic hepatitis, and one (6. 3% ) as Schistosomiasis liver disease. In the two remaining cases (12.5%), no specific diagnosis was confirmed by the liver biopsy. Among the 20 chronic hepatitis B patients ( all of whom presented with abnormal liver function at six month follow - up, high viral load, and alanine aminotransferase (ALT) level lower than twice the upper limit), 13 (65.0% ) had at least moderate intensity hepatic inflammation (greater than or equal to grade Ⅱ) that necessitated antiviral therapy. Furthermore, the majority (69.2%) of these patients represented the 20-40 year-old age category. Conclusion Liver biopsy is an important approach for diagnosing the cause of liver function abnormalities and plays an important role in designing a suitable treatment strategy.关键词
活组织检查,针吸/肝疾病Key words
biopsy, needle/ liver diseases分类
医药卫生引用本文复制引用
沈美蓉,李仲平,丁晓红,储峰,胡德昌..肝穿刺活组织病理检查在肝病诊治中的意义[J].临床肝胆病杂志,2012,28(7):545-547,3.