临床口腔医学杂志2012，Vol.28Issue(5)：265-267,3.DOI:10.3969/j.issn.1003-1634.2012.05.004
猪骨羟基磷灰石对MG63细胞株生物学行为影响的实验研究
Influence of porcine hydroxyapatite on in vitro behavior of MG63 cells
摘要
Abstract
Objective: This study was to determine the effect of PHA on the proliferation and ALP activity of MG63 in order to evaluate in vitro biological properties of PHX. Method: PHA was synthesized with chemical and thermal treatment from porcine cancellous bone and compacted lo form discs on which MG63 cells were planted. 3,7,10 days after planting MG63 cells on PHA discs, CCK-8 assay and ALP activity tests were performed to evaluate the activity of proliferation and in vitro mineralization of cells. Result: Compared to the control, PHA significantly increased the proliferation of MG63 planted on it. Whereas no significant influence on the ALP activity was observed. Conclusion: As a potential bone substitute material. PHA possesses great biocompatibility and bone conductivity.关键词
生物来源羟基磷灰石/MG63细胞株/体外生物学性能Key words
biological hydroxyapatite: MG63 cells/ in vitro biological property分类
医药卫生引用本文复制引用
王冬赟,刘泉,陈泽涛,陈卓凡..猪骨羟基磷灰石对MG63细胞株生物学行为影响的实验研究[J].临床口腔医学杂志,2012,28(5):265-267,3.基金项目
国家自然科学基金面上项目(30973355)广东省自然科学基金(S2011010004978) （30973355）
