临床口腔医学杂志2012，Vol.28Issue(7)：406-409,4.DOI:10.3969/j.issn.1003-1634.2012.07.007
仿生溶液法检测材料生物活性准确性的研究
Simulated body fluid related to implant bioactivity: An in vitro study on dental implants
摘要
Abstract
Objective: To determine whether simulated body fluid (SBF) is suitable to estimate surface bioactivity of dental implants or not. Method: Two types of commercial dental implants (Osseolite()and NanoTiteTM with the aame macro-topography were investigated on apatite formation in vitro by soaking separately with SBF and DMEM for 14 days. The results were studied by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and X-ray photoelectron spectroscopy (XPS). Result: No apatite formation was detected on all samples after soaking in SBF. But globular, uniform apatite-like mineral deposits, accompany with organic molecular attachment was detected on the NanoTite,surface by soaking it in DMEM. Conclusion:SBF does not appear to be suitable to estimate surface bioactivity of a material,but DMEM shows potential for immersion test, aa the influence of organic molecular on the apatite formation.关键词
生物活性/仿生溶液/DMEM培养基Key words
bioaetivity/ simulated body fluid/ DMEM medium分类
医药卫生引用本文复制引用
张少姬,陈卓凡,潘浩波..仿生溶液法检测材料生物活性准确性的研究[J].临床口腔医学杂志,2012,28(7):406-409,4.基金项目
国家自然科学基金面上项目(30973355) （30973355）
