临床口腔医学杂志2012，Vol.28Issue(7)：430-432,3.DOI:10.3969/j.issn.1003-1634.2012.07.017
唇腭裂患儿高级听觉中枢的MRI形态学研究
A MRI study of auditory center of Infants with cleft lip and/or palate
摘要
Abstract
Objective: To investigate possible structural abnormalities of the auditory center of infants with cleft lip anchor palate. Method: Eighteen infants with cleft lip and / or palate, aged from 6 to 24 months, and eighteen normal infants were as control group. Morphological magnetic resonance imaging (MRI) measurements of brain structure of infants were recorded and analyzed using the "FreeSurfer" software package. The data were statistically analyzed using multivariate analysis of covariance (MANCOVA) between groups. Result: No significant group differences were found in right hemisphere, right thalamus and brain stem. However, infants with cleft lip and / or palate had statistically significantly smaller volumes of the left hemisphere, left thalamus and left superior temporal plane (auditory cortex), and significantly decreased thickness of the left superior temporal plane. Conclusion: The auditory center of infants with cleft lip and/or palate may differ from the normal group, and these structural abnormalities may constitute the neurobiological basis of central auditory processing disor-ders (APD).关键词
唇腭裂/磁共振成像/听觉中枢Key words
cleft lip and palate: magnetic resonance imaging/ auditory center分类
医药卫生引用本文复制引用
束煌,杨峰,丁桂聪,向葵,Bradley McPherson,王骥..唇腭裂患儿高级听觉中枢的MRI形态学研究[J].临床口腔医学杂志,2012,28(7):430-432,3.基金项目
深圳市科技局科技计划项目(201003151) （201003151）
