临床输血与检验2012，Vol.14Issue(3)：212-214,3.DOI:10.3969/j.issn.1671-2587.2012.03.005
10例EDTA依赖性假性血小板减少症血小板检测的动态分析
The Dynamic Analysis of PLT Count in EDTA-dependent Pseudothrombocyopenia
郭利利 1顾平 1张葵1
作者信息
- 1. 210008 江苏省南京大学医学院附属鼓楼医院医学检验中心
- 折叠
摘要
Abstract
Objective To investigate the reason of Ethylenediamine tetra-aceticacid (EDTA)-dependent pseu-dothrombocytopenia (EDP) and the method of PLT count in EDP. Methods Blood samples of 10 EDP patients were treated by EDTA-K2 and citrate sodium, respectively. The platelet in blood samples anticoagulated with EDTA were counted at different time points (0,15,30.60 and 120 min). The same patients' blood samples anticoagulated with sodium citrate were tested within 15 min, and the manual counting method was used at the same time. Results No statistically significant difference was found among the results of counting platelets in blood samples anticoagulated with EDTA in 0 min, with sodium derate,or with manual counting method(P>0. 05). There were statistically significant differences between the results of counting platelets in blood samples anticoagulated with EDTA after 15 min and with manual counting method (P<0.05). No statistically significant difference was found between the results of counting platelets in blood samples anticoagulated with sodium citrate and the results of manual counting method (P>0.05). Conclusion The dynamic analysis of PLT count in EDP confirm that EDTA-dependent platelet aggregation is immunological reaction caused by antigen and antibody. The PLT samples of the EDP patients treated with EDTA should be tested immediately or treated with citrate sodium in 15 min or manual counting method.关键词
血小板聚集/EDTA依赖性假性血小板减少症Key words
Platelet aggregation EDTA-dependent pseudo thrombocytopenia分类
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郭利利,顾平,张葵..10例EDTA依赖性假性血小板减少症血小板检测的动态分析[J].临床输血与检验,2012,14(3):212-214,3.
