摘要
Abstract
Objective To analyze the clinical distribution and drug resistance of pseudomonas aeruginosa for 14 kinds of commonly used antibiotics in our hospital in order to provide evidence for rational use of antibiotics. Methods Fractional cultivation was performed in various clinical samples in our hospital with routine methods during October 2010 and March 2012, bacterial I-dentification was performed by V1TEK-2 auto-biological assay machine and drug sensitivity test was carried out by Kirby-Bauer method. Results 1862 strains of pseudomonas aeruginosa were isolated. The isolating rate of sputum was the highest, followed by wound secretion swabs, pus, blood, urine and cerebrospinal fluid. Most of pseudomonas aeruginosa were dispersed in pneumology department, cadre wards, neurosurgery department and ICU. Pseudomonas aeruginosa was highly resistant to ampicillin, ampicillin sodium-sulbactam sodium, cefazolin sodium, compound sulfamethoxazole, gentamicin, piperacillin sodium-lazobactam sodium, cip-rofloxacin and levofloxacin, among them ampicillin, ampicillin sodium-sulbactam sodium and cefazolin sodium was over 90%. Conclusion Pseudomonas aeruginosa is a major iatrogenic pathogenic bacteria, and can easily produce multi-resistance. We should control the use of antibiotics, control hospital infection and strengthen detection of bacterial drug resistance so as to reduce production and diffusion of drug resistant strains.关键词
假单胞菌,铜绿/抗菌药/微生物敏感性试验Key words
Pseudomonad, verdigris/ Antiseptics/ Microbial sensitivity test分类
医药卫生
