中国临床保健杂志2012，Vol.15Issue(5)：472-474,3.DOI:10.3969/J.issn.1672-6790.2012.05.009
中医健脾单元疗法对强直性脊柱炎患者的疗效及对血清骨钙素、抗酒石酸酸性磷酸酶的影响
Chinese medicine Spleen - strengthening Therapy Unit for the curative effect of Ankylosing Spondylitis patients and the influence of BGP, TRACP
摘要
Abstract
Objective To investigate and analyse clinical efficacy of Chinese medicine Spleen-strengthening therapy unit and its effect on serum bone gla protein(BGP) ,tartrate-resistant acid phosphatase (TRACP) .regulatory T cells(Treg) for Ankylosing Spondylitis( AS) patients. Method According to the random number table,60 cases of AS patients were divided into treatment group (34 cases) and control group(26cases). Treatment group adopted Chinese medicine Spleen-strengthening Therapy Unit, namely using Xinfeng capsule (XFC ) plus treatment based on traditional Chinese medicine syndrome(TCM) differentiation and traditional Chinese medicine fumigation treatment. The control group adopted sulfasalazine ( SASP) , with the rest equvilent to the treatment group treated. Using syndrome curative efficacy evaluating criteria of TCM to evaluate its clinical efficacy; Using enzyme-linked immunosorbent assay (ELISA) to determinate BGP,TRACP. Quality of life(QOL) ,symptoms and signs,acute phase reactants index and serum BGP,TRACP of the two groups were compared before and after treatment of AS patients. Result ( 1) Adopted by TCM efficacy evaluation, the total efficiency, significant efficiency-of the treatment group and the control group were 88.2% ,41.2% and 65.4% ,23.3% .which were differences statistically(P ＜0.05). (2) Serum BGP of AS patients after treatment in two groups was increased, while TRACP was decreased, with statistical significance ( P ＜ 0. 01) . Compared with the control group after treatment, serum BGP of the treatment group after treatment were significantly higher,TRACP was lower significantly( P ＜ 0. 01) . Conclusion Curative effect of Chinese medicine Spleen-strengthening therapy unit for AS patient is reliable and better than the control group, which can improve their quality of life and bone metabolism indexes.关键词
脊柱炎,强直性/骨钙素/酸性磷酸酶/中医疗法Key words
Spondylitis,ankylosing/Osteocalcin/ Acid phosphatase/TCM therapy分类
医药卫生引用本文复制引用
汪四海,刘健,杨佳,张金山,万磊,纵瑞凯..中医健脾单元疗法对强直性脊柱炎患者的疗效及对血清骨钙素、抗酒石酸酸性磷酸酶的影响[J].中国临床保健杂志,2012,15(5):472-474,3.基金项目
国家中医药重点学科中医痹病学建设项目(国中医药发[2009]30号) （国中医药发[2009]30号）
安徽省科技厅科研计划项目(09020304046) （09020304046）
安徽省卫生厅中医药科研项目(2009ZY05) （2009ZY05）
安徽中医学院科技创新团队项目(2010TD005) （2010TD005）
