南京医科大学学报(自然科学版)2012,Vol.32Issue(7):965-968,4.
新鲜芦荟对静脉炎治疗效果的实验观察
An experimental observation on using fresh aloe to treat phlebitis
摘要
Abstract
Objective:To evaluate effect of fresh aloe treating phlebitis and find a way to cure phlebitis. Methods: Thirty healthy large-eared New Zealand rabbits were ehozed. Two edged-veins in both ears were set intravenous indwelling needle mimicing real clinic transfusion. The indwelling needles were extracted when phlebitis occurred 5 days after needles setting. Then they were randomly divided into model group, experimental group I and experimental group Ⅱ ,10 rabbits each. Model group did not give any treatment, and the specimens were taken immediately after group divided. The experimental group I were given wet compress with 50% magnesium sulfate. Experimental group Ⅱ were given wet compress with fresh aloe, both groups given extra plastic wrap,4 h each time,2 times per day. After 5 days specimens were taken for pathological observation. Hematoxylin-eosin staining was used to observe pathological changes of vascular intima and beneath connective tissue, transmission electron microscope to observe ultrastructural changes of vascular endothelial cells. Results:There were significant statistical differences in inflammatory effect among three groups (P < 0.001) ;Transmission electron microscope showed that cytoplasm mitochondria and rough endoplasmic reticulum swelling in experimental group I and II was less than that in model group. And the swelling in experimental group Ⅱ was less than that in experimental group I . Conclusion:Fresh aloe and 50% of magnesium sulfate are both useful to treat phlebitis,but fresh aloe treatment is more effective than 50% magnesium sulfate.关键词
静脉留置针/新鲜芦荟/50%硫酸镁/透射电子显微镜Key words
intravenous indwelling needle/fresh aloe/50% magnesium sulfate/transmission electron microscope引用本文复制引用
路雪芹,黄霞,陈传波,景红,吴江..新鲜芦荟对静脉炎治疗效果的实验观察[J].南京医科大学学报(自然科学版),2012,32(7):965-968,4.基金项目
河南省卫生厅医学科技攻关计划项目(201003084) (201003084)