同济大学学报(医学版)2012,Vol.33Issue(3):73-77,5.DOI:10.3969/j.issn1008-0392.2012.03.017
成比例辅助通气与压力支持通气对自主呼吸试验患者效果交叉设计研究
Effects of pressure assist ventilation and pressure support ventilation on spontaneous breathing trial: a cross-over study
摘要
Abstract
Objective To compare the effects of pressure assist ventilation + (PAV + ) mode and pressure support ventilation ( PSV) mode on respiration and circulation in patients undergoing spontaneous breathing trial (SBT). Methods Cross-over design method was applied in this study. All the patients included underwent and completed two SBTs of PAV + and PSV. These two different ventilation modes sequence were set randomly. SBTs were completed in 30 min. Ventilatory and circulatory parameters were monitored and recorded before and after the SBT procedures, including Heart Rate ( HR), mean pressure ( MP), pulse oximetry ( SpO2) , tidal volume (Vte), minute ventilation (MV), mean airway pressure (MAP), rapid shallow breathing index (RSBI), arterial blood gas analysis (ABG). Results Comparing to PSV mode, PAV + mode delivered more Vte and MV during the SBT procedures ( 44.25 ?9.8 ml vs 9.25 ?9.2 ml, P <0.05; 0.88 ?.4 ml vs -0.71 ?1.9 ml, P <0.05, respectively); PAV + mode has lower RSBI at the end of the 30 min SBT procedures (39 ?0 ml vs 53 ?14ml, P=0.041). Other respiration, circulation parameters and ABG at baseline and end of SBT between PAV + and PSV modes showed no significant differences (P > 0.05). Conclusion When patients performed SBT procedures, PAV + mode can deliver more Vte and MV than PAV mode. PAV + mode has lower RSBI at the 30 min of the SBT procedures.关键词
自主呼吸试验/成比例辅助通气/压力支持通气/呼吸浅快指数Key words
spontaneous breath trail/ proportional assist ventilation/ pressure support ventilation/ rapid spontaneous breath index分类
医药卫生引用本文复制引用
王雪英,廖起,彭沪,刘煜昊,王启星,张翔宇..成比例辅助通气与压力支持通气对自主呼吸试验患者效果交叉设计研究[J].同济大学学报(医学版),2012,33(3):73-77,5.基金项目
上海市卫生局科研课题(2009143) (2009143)