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肥胖儿童血浆中orexin-A的表达

贾鲲鹏 赵琳 张红霞 庞随军 李元霞

山西医科大学学报2012,Vol.43Issue(7):525-527,3.
山西医科大学学报2012,Vol.43Issue(7):525-527,3.DOI:10.3969/J.ISSN.1007-6611.2012.07.013

肥胖儿童血浆中orexin-A的表达

Expression of plasma orexin-A in obese children

贾鲲鹏 1赵琳 2张红霞 1庞随军 1李元霞1

作者信息

  • 1. 延安大学附属医院儿科,延安716000
  • 2. 延安大学医学院解剖教研室
  • 折叠

摘要

Abstract

Objective To explore the expression of plasma orexin-A and its correlation with body mass index (BMI) in obese children. Methods Fasting plasma orexin-A concentration was measured and compared in 48 obese children (obese group) and 48 matched healthy children (healthy control group). The correlation between plasma orexin-A concentration and BMI was analyzed. Results The plasma orexin-A concentration in obese group was significantly lower than that in healthy control group (P < 0.05 ). There was a negative correlation between plasma orexin-A concentration and BMI in both obese children and healthy controls(P< 0.01). Conclusion Orexin-A may be involved in the regulation of energy metabolism in obese children,and plasma orexin-A may be closely related with energy intake.

关键词

orexin-A/肥胖/儿童/BMI

Key words

orexin-A/ obesity/ child/ body mass index

分类

医药卫生

引用本文复制引用

贾鲲鹏,赵琳,张红霞,庞随军,李元霞..肥胖儿童血浆中orexin-A的表达[J].山西医科大学学报,2012,43(7):525-527,3.

基金项目

延安大学自然科学专项科研基金资助项目(YD2010-02) (YD2010-02)

山西医科大学学报

OACSTPCD

1007-6611

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