摘要
Abstract
Objectlve To survey the current status of globin generate anemia screening (referred to as the poor) to voluntary acceptance for free premarital examination in Guangxi Nanning. Methods Used hemoglobin electrophoresis to joint blood cells analyzer test average red blood cell volume (MCV) and red blood cell average hemoglobin content (MCH) ,and the red blood cells infiltration brittleness test,examination of all objects for the Mediterranean anemia screening. At the same time, used the multiple polymerase chain reaction (PCR) and reverse spots hybrid method (RDB) to some of the screening,poor results incidence gene diagnosis. Results In the 7 896 cases,there were 1 432 abnormal cases,accounted for 18.14%. There were 166 cases acceptable poor genetic diagnosis,accounting for screening 11. 59% discrepancy. The genetic diagnosis,eliminate poverty in 29 cases,17. 47%. Diagnosed in 137 cases,accounting for 82. 53%. Among them,and alpha to lean in 94 cases ,accounting for 68. 61%;β to poor 42 cases,30. 66% ;α composite β1 case to the poor,accounting for 0. 73%. Conclusion Guangxi Nanning free check-ups to poor people screening high rate,accept to poor gene detection rate is low. The need to enhance propaganda, whereas preconceived notions of guidance on prenatal and postnatal care,improving the population quality to have the important meaning.关键词
婚检人群/珠蛋白生成障碍性贫血/血红蛋白电泳/基因诊断Key words
sheck-ups crowd/the globin generation anemia/ hemoglobin electrophoresis/ genetic diagnosis分类
医药卫生
