现代检验医学杂志2012,Vol.27Issue(2):104-106,3.DOI:10.3969/j.issn.1671-7414.2012.02.037
邯郸地区健康育龄妇女血清抗苗勒氏管激素参考值范围研究
Study on Reference Range of Anti-Mullerian Hormone Level in the Serum for Healthy Women of Childbearing Age in Handan Area
摘要
Abstract
Objective To established the reference range of AMH in the serum by determinating the antt-Mullerian hormone level (AMH) in the serum and the relativity of reproductive age for healthy women of childbearing age in Handan area. Methods Used the Enzyme-linked Immunosorbent Assay (ELISA) to determine the AMH level of serum in the early follicle period (2~5 days menstrual cycle) or corpora luteum metaphase (4~8 days after BBT rised) .meanwhile,need to determine the six reproductive Hormone level of LH,FSH,T,E2,FRL and P for 165 cases with 20~50 years old healthy women of childbearing age. Results The AMH level of serum was distributed in the shape of abnormal status. So the reference range indicated in median (M) and scope. The AMH level of serum in the early follicle period and corpora luteum metaphase bdicated respectively 3. 87(0. 41~10. 69)ng/ml and 4. 64(0. 45—11. 64)ng/ml, which were not with the remarkable differences. The AMH level of serum in early stage and late stage indicated respectively 5.14(0.45~11.64)ng/ml and 2.02(0.41 —9. 03)ng/ml,which would with the remarkable differences (P< 0.001). The reference range of total level for AMH was 4. 55(0. 41~11. 65)ng/ml which will increase in inverse proportion to the age(r=—0. 365,P=0. 000). That was to say,as they grew older, the AMH level would reduce. Conclusion The medical reference range of AMH level in this thesis could be applied to health and medicine practice for clinical diagnosis and treatment of reproduction and infertility of women.关键词
抗苗勒氏管激素/参考值范围/育龄妇女Key words
anti-Mullerian hormone /reference range/woman of childbearing age分类
医药卫生引用本文复制引用
杨小岗,王芳,武佳敏,武春燕,武保乡..邯郸地区健康育龄妇女血清抗苗勒氏管激素参考值范围研究[J].现代检验医学杂志,2012,27(2):104-106,3.基金项目
邯郸市科学技术研究与发展计划资助项目(1023108098-3). (1023108098-3)