现代检验医学杂志2012，Vol.27Issue(3)：89-90,93,3.DOI:10.3969/j.issn.1671-7414.2012.03.029
凝固酶阴性葡萄球菌耐药性及D-试验研究分析
Research and Analysis of Coagulase-Negative Staphylococcus Resistant and D-test
汪莉 1朱海波 1李巧玲 1潘月星 1邓建平1
作者信息
- 1. 黄石市爱康医院检验科,湖北黄石435000
- 折叠
摘要
Abstract
Objective To observate clinical specimens of coagulase-negative staphylococci (CNS) on a variety of antimicrobial drug resistance and the prevalence of inducible clindamycin resistance. Methods Clinical separation 196 strains of CNS were collected from January 2008 to December 2009,they were divided into methicillin-resistant CNS(MRCNS) group and methi-cillin-sensitive CNS (MSCNS) group. The antibiotics sensitivity tests and D-test were carried out according to CLSI standards. WHONET 5. 4 statistic software was usesd to analyse the date. Results MRCNS accounted for 71. 4% of the CNS. Except vancomycin,linezolid and tetracycline, resistance rates of MRCNS gruap to the remaining eight kinds of the antibiotic (penicillin G, oxacillin, chloramphenicol, gentamicin, ciprofloxacin, trimethoprim/sulfamethoxazole, erythromycin and clindamycin) were higher than MSCNS group. There was statistically significant(P<0. 05). The resistant strains to vancomycin, linezolid had not been found. CNS which got resistent to erythromycin and sensitive to clindamycin, the rate of inducible clindamycin resistance was 67. 4%, with MSCNS group higher than MRCNS group,bat there was no statistically significant (P >0. 05). Conclusion Among clinical isolates of CNS,MRCNS detection rate was obviously high and showed multiple drug resistance. What's more, the rate of inducible clindamycin resistance was high in CNS,Therefore,enhancing the conventional resistance testing on CNS and D-test could help guiding clinical medication.关键词
凝固酶阴性葡萄球菌/甲氧西林耐药的凝固酶阴性葡萄球菌/耐药率/D-试验Key words
coagulase-negative staphylococci/MRCNS/resistance rate/D-test分类
医药卫生引用本文复制引用
汪莉,朱海波,李巧玲,潘月星,邓建平..凝固酶阴性葡萄球菌耐药性及D-试验研究分析[J].现代检验医学杂志,2012,27(3):89-90,93,3.
