现代检验医学杂志2012，Vol.27Issue(3)：101-103,3.DOI:10.3969/j.issn.1671-7414.2012.03.033
南京地区变应性鼻炎患者吸入性变应原特异性IgE和总IgE的检测分析
Analysis of Detecting Aeroallergen Specific IgE and IgE Level of Patients with Allergic Rhinitis in Nanjing
王艾丽 1严孝岭 1刘国瑞 1李梅 1虞伟1
作者信息
- 1. 南京军区南京总医院临床中心实验科,南京 210002
- 折叠
摘要
Abstract
Objective To detect the IgE level and aeroallergen specific IgE in order to analyze the characteristic in allergic rhinitis patients of different age. Methods Serum aeroallergen specific IgE antibody and IgE level of patients were detected by velocity scatter nephelometry and immunoblotting. 351 serum samples velocity scatter nephelometry and immunoblotting. 351 serum samples of patients were stratified three age groups :4~ 16 years> 17～40 years old and greater than 40 years old. Results The total IgE positive rate (77. 31%) and IgE level(488. 31 ± 341. 41 IU/ml) in 4~16 years group were significantly higher than that two groups (368. 42 ± 336. 62 IU/ml and 287. 54 ± 315. 06 IU/ml, P<0. 01 and 0. 001). The positive rate of aeroallergen specific IgE antibody in 351 patients serum with allergic rhinitis in order were dermatophagoides pteron-yssinus (81. 48%) , dermatophagoides farinae (81. 2%) , cat-dog epithelia (38. 46%) , cockroach(25. 36%) , pollen mixture (13. Ll%),mugwort(ll. 97%) ,ragweed(ll. 11%),plane tree(7. 12%),mould mixture (6. 27%) and birch(1. 14%). Conclusion The total IgE level in junior group was significant elevated and the sensitive to aeroallergen (dermatophagoides pteronyssinus, dermatophagoides farinae and cat-dog epithelia) was also reinforced. The immunoreactionin of hyper-forty paient group was decreased and It would affect total IgE production. The main aeroallergens (over 20%) of induction different age patients with allergic rhinitis in Nanjing area were mites,cat-dog epithelia and cockroach.关键词
变应性鼻炎/IgE水平/吸入性过敏原特异性IgE抗体Key words
allergic rhinitis/ IgE/ aeroallergen-IgE antibody分类
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王艾丽,严孝岭,刘国瑞,李梅,虞伟..南京地区变应性鼻炎患者吸入性变应原特异性IgE和总IgE的检测分析[J].现代检验医学杂志,2012,27(3):101-103,3.
