现代检验医学杂志2012，Vol.27Issue(3)：104-105,108,3.DOI:10.3969/j.issn.1671-7414.2012.03.034
西宁地区藏族人群HBV DNA基因型的分析
Analysis on Genotyping of Hepatitis B Virus of Tibetan Population in Xining City
摘要
Abstract
Objective To explore the prevalence and genotype of HBV of Tibetans in the Xining area, which would provide the strategy for hepatitis prevention and control. Methods HBV ayw was detected by ELISA method and S gene,C gene fragment were amplificated by PCR method and sequenced, and then the nucleotide sequence homo logy analysis and phylogenetic tree made by MEG A3 software. Results It was shown that 8 cases of ayw subtyp was detected by ELISA, 25 cases were positive by nucleotide sequence determination of HBV S gene sequences, mostly gathered in the D gene of the phylogenetic tree,in the HBV sample of C gene sequences were gathered in the phylogenetic tree of genotype C. Conclusion HBV gene is C/D recombination mostly in population of Tibetans in the Xining area.关键词
HBV/基因型/西宁地区藏族人群Key words
HBV/genotype/Xining area in tibetan population分类
医药卫生引用本文复制引用
闵沛,冯海娥,周肇魁..西宁地区藏族人群HBV DNA基因型的分析[J].现代检验医学杂志,2012,27(3):104-105,108,3.
