陕西医学杂志2012，Vol.41Issue(9)：1223-1225,3.
慢性肺心病患者hs-CRP与NT-ProBNP的检测及临床意义
Clinical significance of hs-CRP and NT-proBNP in patients with chronic pulmonary heart disease
杨侠 1李雅莉 1冯向莉 1张洁 1李妙羡 2张进召 1张秋红1
作者信息
- 1. 西安交通大学医学院第二附属医院呼吸内科,西安,710004
- 2. 西安交通大学医学院第二附属医院临床检验科
- 折叠
摘要
Abstract
Objective:To study the change and the significance of hs-CRP and NT-proBNP in the patients with chronic pulmonary heart disease(PHD). Methods: We recruited 97 patients in the same period after they received a diagnosis of COPD and divided them in to 3 groups. Group A contained 28 patients who had pure COPD. Group B contained 36 patients who had COPD, combined with chronic pulmonaryheart disease during compensatory stage. Group C contained 33 patients who had COPD combined with chronic pulmonary heart disease during decom-pensatory stage. We measured hs-CRP and NT-proBNP in plasma in these 97 patients and then analyzed the differences of its level among the 3 groups. Results: There were significant differences among hs-CRP and NT-proBNP levels in plasma of the 3 groups (P<0. 01). Each group of COPD patients hs-CRP, NT- proBNP serum level were: C group> B group> A group. After the therapy, the hs-CRP, NT-ProBNP serum levels significantly decreased with statistically differences (P<0. 01). Conclusion: The increased hs-CRP levels are correlated with the occurring and developing of chronic pulmonary heart disease. The measurement of plasma NT-proBNP levels in patients with COPD can be used to identify whether they are combined with chronic pulmonary heart disease or heart insufficiency or not.关键词
肺疾病,慢性阻塞性/并发症/肺心病/病因学/肺心病/血液/C反应蛋白质/代谢/NT-ProBNPKey words
Pulmonary disease,chronic obstructive/complications/ Pulmonary heart disease/etiology Pulmonary heart disease/blood/ C-reactive protein/metabolism/@NT-ProBNP分类
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杨侠,李雅莉,冯向莉,张洁,李妙羡,张进召,张秋红..慢性肺心病患者hs-CRP与NT-ProBNP的检测及临床意义[J].陕西医学杂志,2012,41(9):1223-1225,3.
