陕西医学杂志2012，Vol.41Issue(9)：1226-1228,3.
慢性阻塞性肺病100例白细胞介素13及白三烯B4测定及临床意义
The role of interleukin 13 and leukotriene B4 in chronic obstructive pulmonary disease
陈晖 1杨岚2
作者信息
- 1. 西安医学院附属医院呼吸内科
- 2. 西安交通大学医学院第一附属医院呼吸内科,西安,710061
- 折叠
摘要
Abstract
Objective:To contrast the expression of interleukin 13 and leukotriene B4 in chronic obstructive pulmonary disease acute phase, stable and normal people,investigate interleukin 13 and leukotriene B4 in chronic obstructive pulmonary disease in the role. Methods: Detected the content of interleukin 13 and leukotriene B4 in serum of 100 patients with chronic obstructive pulmonary disease in the acute phase and remission by ELISA test (ELISA) and were compared, again compared to 50 normal person . Results: Serum content of interleukin 13 and leukotriene B4 in chronic obstructive pulmonary disease in the acute phase significantly higher than those in remission and normal person(P<0. 01) ,these in the stable phase were higher than normal person(P<0. 05). Conclusion: IL-13 and LTB4 in the pathogenesis of COPD plays an important role in the process, and participates in the airway chronic inflammation of COPD process.关键词
肺疾病,慢性阻塞性/诊断/白细胞介素13/代谢/白三烯B4/代谢Key words
Pulmonary disease ,chronic obstructive/diagnosis Interleukin-13/metabolism Leukotriene B4/metabolism分类
医药卫生引用本文复制引用
陈晖,杨岚..慢性阻塞性肺病100例白细胞介素13及白三烯B4测定及临床意义[J].陕西医学杂志,2012,41(9):1226-1228,3.
