摘要
Abstract
Objective; To investigate the pregnancy outcomes of single-blastoeyst transfer (SBT)in the patients who have high-risk for OHSS. Methods; The clinical data of the patients who received assisted reproductive technology in our center during August 2009 to August 2011 were analyzed retrospectively. The high-risk patients for OHSS who received SBT were for trial group, who received cleavage-stage embryo transfer and freezing embryo transfer for two control groups. The clinical features, controlled ovarian hyperstimulation ( COH ) , pregnancy rate, implantation rate, multiple pregnancy rate, incidence of moderate to severe OIISS were included. Results: The clinical characteristics, COH, embryo formation among the three groups had no statistical difference ( P>0. 05) . Implantation rate , clinical pregnancy rate, multiple pregnancy rate, the rate of occurrence of severe OHSS among the three groups were significantly different (P<0.05). Implantation rale of SBT (51.47% ) was higher than the other two groups, and the clinical pregnancy rate(51. 47% ) was more than frozen-thawed embryo group. Mulliple pregnancy rate of SBT group( 1. 43% ) was significantly lower than the other two groups, and the occurrence of severe OHSS rate (0. 74% ) was lower than the embryo transfer group,with no significant difference compared with the freezing embryo transfer group. Conclusion; Single-blastocyst transfer can ensure a higher pregnancy rate, while significantly reduce the multiple pregnancy rates,but not increase the incidence of OIISS.关键词
单囊胚移植/冻融胚胎移植/卵巢过度刺激综合征/多胎妊娠Key words
Single-blastocyst transfer/Freezing embryo transfer/Ovarian hyperstimulation syndrome/ Multiple pregnancy分类
医药卫生