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卵巢过度刺激综合征高风险患者单囊胚移植的应用

窦倩 孙莹璞 金海霞 王芳 苏迎春

现代妇产科进展2012,Vol.21Issue(4):290-293,4.
现代妇产科进展2012,Vol.21Issue(4):290-293,4.

卵巢过度刺激综合征高风险患者单囊胚移植的应用

Clinical application of single-blastocyst transfer in high-risk patients for ovarian hyperstimulation syndrome

窦倩 1孙莹璞 1金海霞 1王芳 1苏迎春1

作者信息

  • 1. 郑州大学第一附属医院生殖中心,郑州450052
  • 折叠

摘要

Abstract

Objective; To investigate the pregnancy outcomes of single-blastoeyst transfer (SBT)in the patients who have high-risk for OHSS. Methods; The clinical data of the patients who received assisted reproductive technology in our center during August 2009 to August 2011 were analyzed retrospectively. The high-risk patients for OHSS who received SBT were for trial group, who received cleavage-stage embryo transfer and freezing embryo transfer for two control groups. The clinical features, controlled ovarian hyperstimulation ( COH ) , pregnancy rate, implantation rate, multiple pregnancy rate, incidence of moderate to severe OIISS were included. Results: The clinical characteristics, COH, embryo formation among the three groups had no statistical difference ( P>0. 05) . Implantation rate , clinical pregnancy rate, multiple pregnancy rate, the rate of occurrence of severe OHSS among the three groups were significantly different (P<0.05). Implantation rale of SBT (51.47% ) was higher than the other two groups, and the clinical pregnancy rate(51. 47% ) was more than frozen-thawed embryo group. Mulliple pregnancy rate of SBT group( 1. 43% ) was significantly lower than the other two groups, and the occurrence of severe OHSS rate (0. 74% ) was lower than the embryo transfer group,with no significant difference compared with the freezing embryo transfer group. Conclusion; Single-blastocyst transfer can ensure a higher pregnancy rate, while significantly reduce the multiple pregnancy rates,but not increase the incidence of OIISS.

关键词

单囊胚移植/冻融胚胎移植/卵巢过度刺激综合征/多胎妊娠

Key words

Single-blastocyst transfer/Freezing embryo transfer/Ovarian hyperstimulation syndrome/ Multiple pregnancy

分类

医药卫生

引用本文复制引用

窦倩,孙莹璞,金海霞,王芳,苏迎春..卵巢过度刺激综合征高风险患者单囊胚移植的应用[J].现代妇产科进展,2012,21(4):290-293,4.

现代妇产科进展

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1004-7379

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