中国医疗设备2012，Vol.27Issue(6)：27-30,4.DOI:10.3969/j.issn.1674-1633.2012.06.010
二维斑点追踪技术评价肥厚型心肌病左房功能的研究
Evaluation of Left Atrial Function in Patients with Hypertrophic Cardiomyopathy by Two-dimensional Speckle Tracking
摘要
Abstract
Objective To explore the value of two-dimensional speckle tracking in detecting left atrial function in patients with hypertrophic eardiomyopathy (HCM). Methods There were 28 patients with HCM and 30 healthy control subjects enrolled in our study. Left atrial diameter, interventricular septal thickness, left ventricular posterior wall thickness, pressure gradients of left ventricular outflow tract, peak E and A of mitralis(E, A) and E/ A were measured by conventional echocardiography. Left atrial active ejection fraction (LAAEF) and left atrial passive ejection fraction (LAPEF) were calculated with Simpson's method. The longitudinal strain and strain rate curves were acquired in the basal, middle and apical segments of each LA segment (septal, lateral, inferior, and anterior) by two-dimensional speckle tracking. The peak systolic stain, peak systolic stain rate(SRs), peak early diastolic stain rate(SRe) and peak late diastolic strain rate(SRa) were measured in patients and control subjects, while the mean peak strain and mean peak strain rates(mSs, mSRs, mSRe, and mSRa) were also calculated by averaging data in all segments. Results ① Compared with controls group, left atrial diameter, interventricular septal thickness, left ventricular posterior wall thickness, pressure gradients of left ventricular outflow tract, peak A and LAAEF in HCM group were significantly higher (P<0.05) while peak E, E/A and LAPEF significantly decreased(P<0.01). ② mSs, mSRs, and mSRe in HCM group were significantly lower than those in controls group, while mSRa in HCM group was significantly higher than that in controls group. ③ mSRa correlated positively with LAAEF in HCM group(r=0.780,.P<0.01). Conclusion The change of left atrial function of HCM presented as reservoir and conduit functions decreased and pump function increased. Two-dimensional speckle tracking could accurately evaluate the left atrial function and provide important clinical information.关键词
彩色多普勒超声仪/二维斑点追踪技术/肥厚型心肌病/左心房功能评价Key words
color doppler ultrasound system/ two-dimensional speckle tracking/ hypertrophic eardiomyopathy/ left atrial function分类
医药卫生引用本文复制引用
吴文芳,张平洋,吴成权,冉红,张幼祥,董静..二维斑点追踪技术评价肥厚型心肌病左房功能的研究[J].中国医疗设备,2012,27(6):27-30,4.基金项目
江苏省卫生厅科教兴卫工程开发课题(KF2009153) （KF2009153）
南京医科大学科技发展基金面上项目(2010NJMU040). （2010NJMU040）
