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三磷酸腺苷与针刺效应相关性研究评述

陈波 郭义 赵雪 刘阳阳 李忠正 李迎红 郭永明

针刺研究2012,Vol.37Issue(4):338-344,7.
针刺研究2012,Vol.37Issue(4):338-344,7.

三磷酸腺苷与针刺效应相关性研究评述

A Review of Recent Researches on Correlation between ATP and Acupuncture Efficacies

陈波 1郭义 1赵雪 1刘阳阳 1李忠正 1李迎红 2郭永明1

作者信息

  • 1. 天津中医药大学实验针灸学研究中心,天津300193
  • 2. 湖南中医药高等专科学校,株洲412012
  • 折叠

摘要

Abstract

It has been documented that adenosine triphosphate (ATP) is a multifunctional nucleoside triphosphate used in cells, including chemical energy transportation, extra- and intracellular signaling, cell structure maintaining, DNA and RNA synthesis, etc. In the present paper, the authors reviewed studies on the involvement of ATP in different efficacies of acupuncture intervention from the following four aspects.1) ATP release in the stimulated acupoint area is one of the key factors for producing acupuncture analgesia; 2) Acupuncture induced suppression of ATP activity in the central nervous system results in pain relief; 3) ATP application on the human body surface may strengthen the sensation propagation along the meridian; 4) Favorable regulation of acupuncture intervention on the abnormal functional activities of some viscera often accompanies with an increase of ATP content and ATPase activity in the related internal organs. It has been proposed that ATP, Ca2+ and reactive oxygen species (ROS) are closely related each other in the life activities of the organism. Hence, a reasonable regulation on ATP levels in the related organs of the body may be a new approach for raising clinical therapeutic effects of acupuncture therapy.

关键词

三磷酸腺苷/针刺效应/临床疗效/针刺镇痛/循经感传/内脏功能调节

Key words

Adenosine triphosphate/ Acupuncture therapy/ Clinical efficacy/ Acupuncture analgesia/Sensation propagation along the meridian/ Visceral functional regulation

分类

生物科学

引用本文复制引用

陈波,郭义,赵雪,刘阳阳,李忠正,李迎红,郭永明..三磷酸腺苷与针刺效应相关性研究评述[J].针刺研究,2012,37(4):338-344,7.

基金项目

国家自然科学基金资助项目(No.81072881、81173204)、教育部高等学校博士学科点专项科研基金资助课题(20101210110007) (No.81072881、81173204)

针刺研究

OACSCDCSTPCD

1000-0607

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