中国当代儿科杂志2012，Vol.14Issue(8)：604-606,3.
儿童良性黑棘皮病与代谢异常
Childhood benign acanthosis nigricans and metabolic abnormality
米热古丽·买买提 1徐永杰 1徐佩茹1
作者信息
- 1. 新疆医科大学第一附属医院,新疆 乌鲁木齐 830054
- 折叠
摘要
Abstract
Objective To observe the relationship of childhood benign acanthosis nigricans to anthropometric and metabolic indexes, with the aim of studying the association between childhood benign acanthosis nigricans and metabolic diseases. Methods A retrospective analysis was performed on the clinical data of 29 children who presented with benign acanthosis nigricans between February 2007 and October 2011. Thirty-two age-, sex- and ethnic-matched normal children were selected as control group. The two groups were compared according to obesity (body mass index, waist-to-hip ratio, body fat content and body fat percentage) and metabolic indexes (blood glucose, insulin level and blood lipids). Results Body mass index, body fat content, body fat percentage, waist-to-hip ratio, fasting blood glucose, insulin level and triglyceride in the 29 patients with benign acanthosis nigricans were higher than in the control group ( P <0. 05) , but the level of high-density lipoprotein in the 29 patients was lower than in the control group (P<0.05). Of the 29 patients, 16 had impaired glucose tolerance and 3 were diagnosed with diabetes ( 1 case with type 1, two cases with type 2). Conclusions Childhood benign acanthosis nigricans is closely associated with obesity, insulin resistance and dyslipidemia.关键词
黑棘皮病/胰岛素抵抗/肥胖/儿童Key words
Acanthosis nigricans/ Insulin resistance/ Obesity/ Child分类
医药卫生引用本文复制引用
米热古丽·买买提,徐永杰,徐佩茹..儿童良性黑棘皮病与代谢异常[J].中国当代儿科杂志,2012,14(8):604-606,3.
