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白藜芦醇外涂美白功效及安全性的临床观察

贾丽丽 李远宏 吴严 李晓红 刘效远

中国美容医学2012,Vol.21Issue(9):1340-1342,3.
中国美容医学2012,Vol.21Issue(9):1340-1342,3.

白藜芦醇外涂美白功效及安全性的临床观察

Clinical observation the whitening efficacy and safety of resveratrol

贾丽丽 1李远宏 2吴严 2李晓红 2刘效远1

作者信息

  • 1. 吉林大学第四医院皮肤科 吉林长春130011
  • 2. 中国医科大学附属第一医院皮肤科暨卫生部免疫皮肤病学重点实验室辽宁沈阳110001
  • 折叠

摘要

Abstract

Objective To investigate the whitening efficacy and safety of resveratrol on human facial skin. Methods Forty healthy female volunteers were enrolled in this study.They were randomly assigned into treatment group (20 cases) and control group (20 cases).Treatment group and control group were respectively received resveratrol cream and base cream,for 12 consecutive weeks.Before and after treatments,skin color and water content were measured. Results After treatment with resveratrol,the mean melanin index (Ml) value decreased obviously compared with pretreatment,and the Ml difference value of treatment group was significantly lower than that of control group.The erythema index and water content remained unchanged pre- and post-treatment.The skin pigmentation of about 65% volunteers assessed by a dermatologist obtained moderate to obvious improvement and approximate 60% volunteers rated satisfactory or very satisfactory. There were no side-effects. Conclusion The topical resveratol has whitening effect on skin,without any side effects.

关键词

白藜芦醇/美白/黑素指数

Key words

resveratrol/ whitening/ melanin index

分类

医药卫生

引用本文复制引用

贾丽丽,李远宏,吴严,李晓红,刘效远..白藜芦醇外涂美白功效及安全性的临床观察[J].中国美容医学,2012,21(9):1340-1342,3.

基金项目

2010年教育部高等学校博士学科点专项科研基金资助课题(编号:20102104120007) (编号:20102104120007)

中国美容医学

1008-6455

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