中国美容医学2012，Vol.21Issue(9)：1366-1368,3.
钙泊三醇倍他米松和卤米松软膏治疗寻常型白癜风的自身对照研究
Calcipotriol betam ethasone ointment and Halometasone Cream in the treatment of vitiligo vulgaris: a self-controlled, parallel group study
摘要
Abstract
Objective To assess the clinical eficacy and safety of calcipotriol betam ethasone and halometasone cream in Chinese patients with stable vitiligo vulgaris. Methods In this self-controlled parallel group study. 68 vitiligo with symmetrical white macules were recruited from the out-patient clinic. The left lesions receive alcipotriol betamethasone ointment once daily in the evening, and the right lesion receive halometasone cream once daily in the morning. The safety and eficacy of the two regimens were evaluated on week 12 after the first dosage. Results Atier 12 weeks of treatment, mean repigmentation was observed in 15.51% ±0.13%for the left lesions , 12.86%±0.22% for the right group. There is significant difference between calcipotriol betam ethasone and halometasone cream (T=2.013,P<0.05). The ratio of side-effects was 1.4%±0.02% in the calcipotriol betam ethasone group, and 2.9%±0.01% in the halometasone cream group . Significant difference is seen among the two groups (x2=4.345, P<0.05). Main side adverses include mild to moderate skin reactions,such as pruritus. Conclusions Once daily calcipotriol betamethasone ointment is an effective, safe,convenient treatment with a rapid onset of action for stable vitiligo vulgaris in Chinese patients.in关键词
白癜风/钙泊三醇倍他米松/卤米松/临床疗效Key words
vitiligo/ calcipotriol betam ethasone/ halometasone/ clinical efficacy分类
医药卫生引用本文复制引用
李强,高天文,焦彬,翟佳,罗莉,马雅楠,李翠翠,马翠玲,刘斌,李春英..钙泊三醇倍他米松和卤米松软膏治疗寻常型白癜风的自身对照研究[J].中国美容医学,2012,21(9):1366-1368,3.基金项目
国家自然科学基金(30972642,81130032) （30972642,81130032）
