中国美容医学2012,Vol.21Issue(z2):102-103,2.
柳氮磺胺吡啶联用丽珠肠乐对溃疡性结肠炎结肠组织中防御素的表达的影响和意义
The Impact of Sulfasalazine combined with Lizhuchangle on β Defensin-2 Expression in Colonic Tissue of Ulcerative Colitis
摘要
Abstract
Objective: To investigate the impact of sulfasalazine combined with lizhuchangle on p defensin-2 expression in colonic tissue of ulcerative colitis. Methods: 116 cases of ulcerative colitis patients in our hospital were randomly divided into two groups: 56 cases of sulfasalazine group and 60 cases of sulfasalazine combined with lizhuchangle group. Results: After treatment, compared with sulfasalazine, the cases of focal hemorrhage in sulfasalazine combined with lizhuchangle were reduced significantly (P <0.05). Compared with the sulfasalazine, β defensin-2 expression was significantly reduced in sulfasalazine combined with lizhuchangle after treatment (P <0.05). Conclusion: Sulfasalazine combined with lizhuchangle can significantly reduce p defensin-2 exprssion in colon tissue and treat ulcerative colitis.关键词
柳氮磺胺吡啶/丽珠肠乐/溃疡性结肠炎/β防御素-2Key words
Sulfasalazine/Lizhuchangle/ Ulcerative Colitis/ β Defensin-2分类
医药卫生引用本文复制引用
刘大鹏..柳氮磺胺吡啶联用丽珠肠乐对溃疡性结肠炎结肠组织中防御素的表达的影响和意义[J].中国美容医学,2012,21(z2):102-103,2.