中国实用内科杂志2012，Vol.32Issue(8)：617-620,后插25,5.
隐源性机化性肺炎随访期影像学演变23例分析
Radiologic development of cryptogenic organizing pneumonia during follow-up: an analysis of 23 cases
孙渊 1肖永龙 1周科峰 2蔡后荣 1张德平1
作者信息
- 1. 南京中医药大学中西医结合鼓楼临床学院呼吸科,南京210008
- 2. 南京中医药大学中西医结合鼓楼临床学院放射科,南京210008
- 折叠
摘要
Abstract
Objective To conduct a retrospective analysis on the radiologic development during follow-up in patients who had eryptogenie organizing pneumonia (COP) treated or not treated with corticosteroids. Methods We recruited 42 patients with COP diagnosed clinically and radiologically in addition to laboratory examinations and biopsy from November 2004 to July 2011. The radiologic and clinical development during follow-up visits in 23 patients was analyzed. Results Twenty-three patients (12 males and 11 females) who were aged 51 (range; 16 ~80) years were followed-up for an average of 6. 2 months ( range ;30 days ~ 14 months). On initial presentation, common features of pulmonary anomaly on high-resolution computed tomography were multiple patchy attenuation, patchy air-space consolidation and reticulation. The consolidation lesions, distributed randomly or along with bronchial vessels, were mainly located in subpleural regions and bilateral lower lobes where ground-glass opacification, traction bronchiectasis and stripe-like opacities might be common while migratory lesions could be found in certain cases. Of 20 cases treated with corticosteroids, 1 had complete resolve, 17 presented diminished high-density images including consolidation and ground-glass opacification,3 showed decreased region of reticulation,! did not show evidence of changes in reticulation,2 developed emerging reticulation and 2 relapsed. All three cases not treated with corticosteroids presented significantly diminished lesions. Conclusion Twenty cases (91% ) with COP respond well to corticosteroids. The majority of patients (82% ) have remaining foci on CT during follow-up. Certain cortico-steroid-naive patients may resolve spontaneously. Follow-up chest CT may be useful to assessment of treatment outcomes and prognosis.关键词
隐源性机化性肺炎/随访/高分辨率CTKey words
eryptogenie organizing pneumonia/follow-up/high-resolution computed tomography分类
医药卫生引用本文复制引用
孙渊,肖永龙,周科峰,蔡后荣,张德平..隐源性机化性肺炎随访期影像学演变23例分析[J].中国实用内科杂志,2012,32(8):617-620,后插25,5.
