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61例胃肠道间质瘤的诊治经验及病理学特点分析

黄先龙 袁联文

中国现代手术学杂志2012,Vol.16Issue(2):104-106,3.
中国现代手术学杂志2012,Vol.16Issue(2):104-106,3.

61例胃肠道间质瘤的诊治经验及病理学特点分析

Managements and Pathologic Characteristics of the Gastrointestinal Stromal Tumors in 61 Cases

黄先龙 1袁联文2

作者信息

  • 1. 湖南省华容县人民医院普通外科,岳阳414200
  • 2. 中南大学湘雅二医院老年外科,长沙410011
  • 折叠

摘要

Abstract

Objective To explore the surgical experiences and the pathologic characteristics of gastrointestinal stromal tumors (GIST). Method The clinicopathologie features of 61 patients who were diagnosed as GIST were analyzed retrospectively. Results In the 61 patients, CD117 was positive in 60 cases (98.4% ). CD34 was positive in 49 cases (80. 3% ). Actin was positive in 37 cases (60. 7% ) and S-100 positive in 12(19.7%). 61 patients were followed up for an average of 3. 2(0. 5 - 5 ) years, including 43 patients were followed up over three years. The 3-year overall survival rate was 88.4% (38/43). According to the 2002 Fletcher's risk grading standards of GIST, there were very low risk group 9. 8% (6/61), low-risk group 24.6% (15/61), medium risk group 19.7% (12/61) and high risk group 45.9% (28/61). And the 3-year survival rate of these four groups had no significant difference (P > 0. 05). Conclusions GIST is located mainly in stomach. Positive CD117 is the standard diagnostic reference for GIST. Radical excision is the first choice in the clinical treatment principle.

关键词

胃肠道间质肿瘤/病理学,临床

Key words

gastrointestinal stromal tumors/ pathology, clinical

分类

医药卫生

引用本文复制引用

黄先龙,袁联文..61例胃肠道间质瘤的诊治经验及病理学特点分析[J].中国现代手术学杂志,2012,16(2):104-106,3.

中国现代手术学杂志

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