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抗原表位鉴定方法的研究进展

文雪霞 陈化兰 熊永忠 王秀荣

中国畜牧兽医2012,Vol.39Issue(7):66-70,5.
中国畜牧兽医2012,Vol.39Issue(7):66-70,5.

抗原表位鉴定方法的研究进展

Research Advance in Epitope Identification Methods

文雪霞 1陈化兰 1熊永忠 1王秀荣1

作者信息

  • 1. 中国农业科学院哈尔滨兽医研究所,农业部动物流感重点开放实验室,兽医生物技术国家重点实验室,黑龙江哈尔滨150001
  • 折叠

摘要

Abstract

An epitope is the part of an antigen that is combined with lymphocyte surface receptors. Generally, it is composed of several amino acid residues or their spatial structure. It is the material basis of the immune response) and its nature decides the specificity of antigen. Epitope identification methods include peptides scanning techniques, amino acid mutagenesis techniques, X-ray or nuclear magnetic resonance, mass spectrometry. peptide phage display technology and bioinformatics prediction. The common approaches for epitopes study in recent years were reviewed in this paper.

关键词

抗原表位/鉴定方法/研究进展

Key words

epitope/ identification methods/ research advance

分类

农业科技

引用本文复制引用

文雪霞,陈化兰,熊永忠,王秀荣..抗原表位鉴定方法的研究进展[J].中国畜牧兽医,2012,39(7):66-70,5.

基金项目

哈尔滨市科技创新人才研究专项(RC2011XK002029) (RC2011XK002029)

公益行业科研专项(200903055). (200903055)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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