中国畜牧兽医2012，Vol.39Issue(8)：145-148,4.
哺乳动物DNA甲基化研究进展
Research Progress on the Methylation in Mammals
摘要
Abstract
DNA methylation is the common base modification in the eukaryotic genome and is an important epigenetic mechanism. Methylation at the five-carbon of cytosine is a reversible process that can directly influence gene activity and the reaction is catalyzed by a family of DNA methyltransferases(DNMTs). DNA methylation is essential for normal mammals development and plays an important role in the affects a wide range of essential biological processes, and it includes silencing of transposable elements, inactivation of genes, maintenance of chromosomal integrity, X chromosome inactivation.and transcriptional regulation of a large number of genes and so on.关键词
DNA甲基化/DNA甲基化转移酶/表观遗传/沉默Key words
DNA methylation/DNA methyltransferases /epigenetic/0silencing分类
生物科学引用本文复制引用
杨春,邢秀梅..哺乳动物DNA甲基化研究进展[J].中国畜牧兽医,2012,39(8):145-148,4.基金项目
国家科技基础条件平台中心(家养动物种质资源平台)项目. （家养动物种质资源平台）
