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J亚型禽白血病病毒感染黄鸡病毒血症和抗体反应动态的研究

王小芬 刘雪美 廖亚琳 吴晓婵 廖明 曹伟胜

中国畜牧兽医2012,Vol.39Issue(8):174-178,5.
中国畜牧兽医2012,Vol.39Issue(8):174-178,5.

J亚型禽白血病病毒感染黄鸡病毒血症和抗体反应动态的研究

Research of Dynamics of Viremia and Antibody Responses of Yellow Chicken Infected by Avian Leukosis Virus Subgroup J

王小芬 1刘雪美 1廖亚琳 1吴晓婵 1廖明 1曹伟胜1

作者信息

  • 1. 华南农业大学兽医学院,农业部动物疫病防控重点开放实验室,广东广州510642
  • 折叠

摘要

Abstract

The dynamics of viremia.ALV-J antibody response in yellow chickens and p27 antigen shedding in cloacal swabs were examined respectively after the 11-day-old yellow chicken embryos were inoculated with hemangioma related ALV-J SCAU-HN06 isolate via allantoic cavity. The results showed that viremia could be detected as early as 1 week post hatch,there was a viremia peak at 7 week,and the positive rate of viremia remained more than 80% continuously since 9 week. ALV-J antibody response could be detected as early as 6 week by ELISA.the positive rate of antibody was no more than 33. 3% during the trial. The positive rate of p27 antigen in cloacal shedding rised quickly, reached peak at 3 week, then kept at high level. The study suggested that ALV-J isolate infection via egg inoculation could result in persistent viremia and immunotoleranee. The study provided the basis for ALV-J control and eradication in yellow chickens.

关键词

J亚群禽白血病病毒/黄鸡/病毒血症/动态

Key words

subgroup J avian leukosis virus(ALV-J)/ yellow chicken/ viremia/ dynamic

分类

农业科技

引用本文复制引用

王小芬,刘雪美,廖亚琳,吴晓婵,廖明,曹伟胜..J亚型禽白血病病毒感染黄鸡病毒血症和抗体反应动态的研究[J].中国畜牧兽医,2012,39(8):174-178,5.

基金项目

公益性行业(农业)科研专项(201203055) (农业)

NSFC-广东联合基金(U0831002) (U0831002)

国家肉鸡产业技术体系项目(CARS-24-G09) (CARS-24-G09)

广东省自然科学基金项目(S2011010001946). (S2011010001946)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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