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罗汉果叶不同溶剂提取物对DPPH自由基的清除作用研究

杨艳芳 朱艳平 肖梦媛 陈清杰 吴和珍

中国药房2012,Vol.23Issue(19):1729-1730,2.
中国药房2012,Vol.23Issue(19):1729-1730,2.DOI:10.6039/j.issn.1001-0408.2012.19.01

罗汉果叶不同溶剂提取物对DPPH自由基的清除作用研究

Scavenging Effect of Different Extracts of the Leaf of Siraitia grosvenorii on Free Radical DPPH

杨艳芳 1朱艳平 2肖梦媛 2陈清杰 2吴和珍2

作者信息

  • 1. 湖北中医药大学中药资源与中药复方教育部重点实验室,武汉 430065
  • 2. 湖北中医药大学药学院,武汉430065
  • 折叠

摘要

Abstract

OBJECTIVE: To study on scavenging activity of different extracts of the leaf of Siraitia grosvenorii on free radical DPPH. METHODS: The alcohol extracts from the leaf of S. grosvenorii were divided into four parts including petroleum ether part, ethyl acetate part, n-buryl alcohol part and water part by systematic solvent method. The antioxidant activity of the four parts were determined by free radical DPPH systematic method, and compared with gallic acid and ascorbic acid. RESULTS: Half rate of scavenging effect on free radical DPPH by the extracts from the petroleum ether part, the ethyl acetate part, the n-butyl part and the water part of the leaf of S. grosvenorii reflected on IC50, which were 16.250 mg crude drug·mL‐1, 0.554 mg crude drug·mL‐1, 0.596 mg crude drug · mL‐1 and 0.267 mg crude drug · mL‐1, respectively. CONCLUSION: Antioxidant activity of the four extracts from S. grosvenorii does exist, moreover, the water extract has the strongest effect.

关键词

罗汉果/二苯基苦基苯肼/抗氧化活性

Key words

Siraitia grosvenorii/ DPPH/ Antioxidant activity

分类

医药卫生

引用本文复制引用

杨艳芳,朱艳平,肖梦媛,陈清杰,吴和珍..罗汉果叶不同溶剂提取物对DPPH自由基的清除作用研究[J].中国药房,2012,23(19):1729-1730,2.

基金项目

中国博士后科学基金资助项目(20100471126) (20100471126)

中国药房

OACSCDCSTPCD

1001-0408

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