中国药房2012，Vol.23Issue(20)：1856-1857,2.DOI:10.6039/j.issn.1001-0408.2012.20.12
中等剂量熊去氧胆酸治疗原发性胆汁性肝硬化的临床观察
Clinical Observation of Medium Dose of Ursodeoxycholic Acid for Primary Biliary Cirrhosis
胡西百合提 1贾芸1
作者信息
- 1. 新疆维吾尔自治区中医医院,乌鲁木齐830026
- 折叠
摘要
Abstract
OBJECTIVE: To observe clinical efficacy of moderate dose of ursodeoxycholic acid for primary biliary cirrhosis. METHODS: 196 patients with primary biliary cirrhosis were divided into 2 groups. 95 cases in the control group were given routine symptomatic therapy (liver protection, detoxification, diuretic, antibacterial). 101 cases in treatment group were additionally given moderate dose of ursodeoxycholic acid on the basis of symptomatic therapy. A course of treatment lasted for 1 month. The therapeutic efficacy and liver function of 2 groups were investigated after 3 treatment courses. RESULTS: After 3 treatment courses, total effective rate of treatment group (79.2%) was significantly higher than that of control group (60.0%), there was statistical significance (P<0.01); Results of liver function test showed that ALT and AST of treatment group decreased significantly (P< 0.01), was close to normal levels, GGB, ALT and TBA index hadn't returned to normal range, but was lower than before treatment (P<0.0l). CONCLUSION: The medium dose of ursodeoxycholic acid has obvious effect on primary biliary cirrhosis.关键词
原发性胆汁性肝硬化/熊去氧胆酸/临床观察Key words
Primary biliary cirrhosis/ Ursodeoxycholic acid/ Clinical observation
分类
医药卫生引用本文复制引用
胡西百合提,贾芸..中等剂量熊去氧胆酸治疗原发性胆汁性肝硬化的临床观察[J].中国药房,2012,23(20):1856-1857,2.
