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黄柏及其炮制品水提物体内、外抑菌作用研究

林海 龚又明 邓广海

中国药房2012,Vol.23Issue(31):2900-2902,3.
中国药房2012,Vol.23Issue(31):2900-2902,3.DOI:10.6039/j.issn.1001-0408.2012.31.07

黄柏及其炮制品水提物体内、外抑菌作用研究

Bacteriostatic Effects of Phellodendron chinense and Its Processed Products Water Extract in Vitro and in Vivo

林海 1龚又明 1邓广海1

作者信息

  • 1. 广东省中医院药学部,广州 510120
  • 折叠

摘要

Abstract

OBJECTIVE: To study the bacteriostatic effects of Phellodendron chinense and its processed products water extract in vitro and in vivo. METHODS: The sensitivity of P. chinense and its processed products water exteact to various germ strains was detected by in vitro bacteriostatic test. Effects of P. chinense (0.46,0.92,1.84 g·kg-1) and its processed products water extract on mortality of mice with peritoneal injection of Staphylococcus aurous were observed by in vivo bacteriostatic test. RESULTS: P. chinense and its processed products had varying degrees of bacteriostatic activity in vitro and in vivo, and the processed products with wine showed the best inhibitory effect. The processed products with wine 1.84 g·kg-1 had the best effect on improving the mortality of mice with peritoneal injection of Staphylococcus aurous. CONCLUSION: It is scientific that the processed products with wine of P. chinense are used for the treatment of bacterial diseases.

关键词

黄柏/体内抑菌/体外抑菌/炮制

Key words

Phellodendron chinense/ Bacteriostatic effect in vitro/ bacteriostatic effect in vivo/ Processing

分类

医药卫生

引用本文复制引用

林海,龚又明,邓广海..黄柏及其炮制品水提物体内、外抑菌作用研究[J].中国药房,2012,23(31):2900-2902,3.

中国药房

OACSCDCSTPCD

1001-0408

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