中国药业2012，Vol.21Issue(11)：14-15,2.
近红外光谱技术用于川红活血胶囊提取过程的研究
Studies on NIR Spectroscopy of Chuanhong Huoxue Capsules Extraction Process
摘要
Abstract
Objective To establish a method for on-site analysis of paeoniilorin content of Chuanhong Huoxue Capsules Extracting process with acousto optictunable filter(AOTF)-near infrared (NIR) spectroscopy technology. Methods To collect fluid samples on-site and to establish database of paeonifloxin content and NIR spectroscopy; then calibration model of NIR spectroscopy - paeoniflorin content was established with partial least squares (PLSl);to verify the calibration model prediction with samples collected online. Results Correlation coefficients R2 between calibration model and inside data were 0. 992 and 0.995; average relative deviations of prediction and outside sample were 4. 25%; method precision RSD were 2. 70%; sample stabilities in 5 h were 2. 07%; forecast recoveries were 96. 7%. Conclusion NIR spectroscopy for on - site analysis of paeoniflorin content of Chuanhong Huoxue Capsules Extracting process is fast, direct, and to achieve on - site analysis.关键词
声光可调滤光器/近红外光谱/川红活血胶囊/在线分析Key words
AOTF: NIR/ Chuanhong Huoxue Capsules/ on - site analysis分类
医药卫生引用本文复制引用
耿炤,胡浩武,李胜华,王木兰,梅玲华,孙晓波..近红外光谱技术用于川红活血胶囊提取过程的研究[J].中国药业,2012,21(11):14-15,2.基金项目
国家"重大新药创制"科技重大专项,项目编号:2009ZX09313-029. （）
