中国卒中杂志2012，Vol.7Issue(6)：466-471,6.
三维时间飞跃法磁共振血管成像原始图像评估脑微出血病灶的应用价值
Application Value of Source Images by Three-Dimensional Time-of-Flight Magnetic Resonance Angiography in Detecting Cerebral Microbleeds
隋滨滨 1高培毅 2林燕 1薛静 2沈宓 1王辉 2王琼1
作者信息
- 1. 1100050北京,首都医科大学附属北京天坛医院放射科
- 2. 北京市神经外科研究所
- 折叠
摘要
Abstract
Objective To study the value of source images of three dimensional time-of-flight magnetic
resonance angiography(3D-TOF MRA) in detecting cerebral microbleeds(CMBs) in brain
parenchyma.
Methods Two hundred and eighty patients who were suspected to have microbleeding lesions were
recruited. T2* gradient recall echo(GRE) sequence and 3D-TOF MRA sequences were performed
after routine magnetic resonance(MR) head imaging were performed. Numbers, location, and scales
of CMBs on 3D-TOF MRA axial source images and T2*GRE images were compared.
Results Seven-five cases were proved to have CMBs by T2*GRE sequence. Nine cases which
could not be compared were excluded. On T2*GRE images, three hundred and thirty eight CMBs
were found with 50 cases as grade 1,10 cases as grade 2, and 6 cases as grade 3. On 3D-TOF MRA
source images, two hundred and forty two CMBs were found with 1 lcases as grade 0, 40 cases as
grade 1,12 cases as grade 2, and 3 cases as grade 3. Paired-sample t test showed that there were
significant difference between CMBs found by two methods at cortical/subcortical area(P=0.000),
thalami(P=0.001), and cerebellum(P=0.039), while no significant difference were found between
CMBs found by two methods at basal ganglia(P=0.581) and brain stem(P=0.211). Consistency of
two different sequences showed Kappa value was 0.494(P=0.092).
Conclusion Source images of 3D-TOF MRA can be used to detect CMBs. Though CMBs on
3D-TOF MRA source images were not as clear as those on T2*GRE images, when T2*GRE images
are absent, 3D-TOF MRA source images may be helpful to display microbleeds lesions and suggest
further examination.
关键词
三维时间飞跃法/磁共振血管成像/微出血,脑Key words
Three-dimensional time of flight/ Magnetic resonance angiography/ Microbleeds, brain引用本文复制引用
隋滨滨,高培毅,林燕,薛静,沈宓,王辉,王琼..三维时间飞跃法磁共振血管成像原始图像评估脑微出血病灶的应用价值[J].中国卒中杂志,2012,7(6):466-471,6.
