中华医学杂志（英文版）2012，Vol.125Issue(17)：3033-3038,6.DOI:10.3760/cma.j.issn.0366-6999.2012.17.012
Prevalence and risk factors of chronic post-thoracotomy pain in Chinese patients from Peking Union Medical College Hospital
Prevalence and risk factors of chronic post-thoracotomy pain in Chinese patients from Peking Union Medical College Hospital
WANG Hai-tang 1LIU Wei 1LUO Ai-lun 1MA Chao 2HUANG Yu-guang1
作者信息
- 1. Department of Anesthesiology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medicine Science,Beijing 100730,China
- 2. Department of Anatomy,Histology and Embryology,Peking Union Medical College,School of Basic Medicine,Chinese Academy of Medical Sciences,Institute of Basic Medical Sciences,Beijing 100005,China
- 折叠
摘要
Abstract
Background In clinical practice,the mechanisms underlying chronic post-surgical pain (CPSP) remain insufficientlyunderstood.The primary goals of this study were to determine the incidence of chronic pain after thoracic surgery and to identify possible risk factors associated with the development of chronic post-thoracotomy pain in Chinese patients.The secondary goal was to determine whether the difference between pre-and post-operative white blood cell (WBC) counts could predict the prevalence of CPSP after thoracotomy.The impact of chronic pain on daily life was also investigated.Methods We contacted by phone 607 patients who had undergone thoracotomy at our hospital during the period February 2009 to May 2010.Statistical comparisons were made between patients with or without CPSP.Results Results were ultimately analyzed from 466 qualified patients.The overall incidence of CPSP was 64.5％.Difference between pre-and post-operative WBC counts differed significantly between patients with or without CPSP (P＜0.001) and was considered as an independent risk factor for the development of CPSP following thoracotomy (P＜0.001).Other predictive factors for chronic pain included younger age (＜60 years,P ＜0.001),diabetes mellitus (P=0.023),acute post-operative pain (P=0.005) and the duration of chest tube drainage (P ＜0.001).At the time of interviews,the pain resulted in at least moderate restriction of daily activities in 15％ of the patients,of which only 16 patients had paid a visit to the doctor and only three of them were satisfied with the therapeutic effects.Conclusions Chronic pain is common after thoracotomy.WBC count may be a new independent risk factoring surgical patients during peri-operative period.Besides,age,diabetes mellitus,acute post-operative pain,and duration of chest tube drainage may also play a role in chronic post-surgical pain occurrence.关键词
chronic post-surgical pain/ risk factor/ white blood cell count/ thoracotomy/ incidenceKey words
chronic post-surgical pain/ risk factor/ white blood cell count/ thoracotomy/ incidence引用本文复制引用
WANG Hai-tang,LIU Wei,LUO Ai-lun,MA Chao,HUANG Yu-guang..Prevalence and risk factors of chronic post-thoracotomy pain in Chinese patients from Peking Union Medical College Hospital[J].中华医学杂志（英文版）,2012,125(17):3033-3038,6.
