中药材2012，Vol.35Issue(3)：357-360,4.
蛴螬脂溶性成分的气相色谱-质谱联用分析及抗炎、镇痛活性研究
Analysis of Liposoluble Constituents in Holotrichia diomphalia by GC-MS and Investigation Their Anti-inflammatory and Analgesic Activities
摘要
Abstract
Objective:To analysis liposoluble constituents of Holotrichia diomphalia by GC-MS and measure their anti-inflammatory and analgesic activities. Methods: The composition of liposoluble constituents were determined by GC-MS. The dimethylbenzene-induced mice inflammatory models were established. The pain models were obtained by hot plate and acetic acid in mice. Results: Twenty-two components were identified from the petroleum ether extract of Holotrichia diomphalia. The major components were oleic acid,palmitic acid and palmitoleic acid. The petroleum ether extract was able to significantly inhibit the mice ear edema induced by dimethyl-benzene. The pain in mice caused by acetic acid and hot plate were evidently suppressed by the petroleum ether extract Conclusion:The petroleum ether extract of Holotrichia diomphalia has obvious anti-inflammation and analgesic effects.关键词
蛴螬/气相色谱-质谱联用/抗炎/镇痛Key words
Holotrichia diomphalia Bates/GC-MS/Anti-inflammatory/Analgesic分类
医药卫生引用本文复制引用
裴克,曹蔚,郭倩倩,谢艳华,贺中民,王四旺..蛴螬脂溶性成分的气相色谱-质谱联用分析及抗炎、镇痛活性研究[J].中药材,2012,35(3):357-360,4.基金项目
陕西省“13115”科技创新工程技术研究中心基金项目(S210ZDGC105) （S210ZDGC105）
陕西省药监局中药材标准项目(2009003) （2009003）
