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北京石景山区老年人群牙周炎与代谢综合征的相关性探讨

于卓人 刘丽笙 栾庆先 王兴宇 李蓬 沙月琴 刘曦

北京大学学报(医学版)2012,Vol.44Issue(4):633-638,6.
北京大学学报(医学版)2012,Vol.44Issue(4):633-638,6.DOI:10.3969/j.issn.1671-167X.2012.04.031

北京石景山区老年人群牙周炎与代谢综合征的相关性探讨

Correlation between periodontitis and metabolic syndrome of the middle-aged and aged population in Shijingshan community of Beijing

于卓人 1刘丽笙 2栾庆先 1王兴宇 2李蓬 3沙月琴 1刘曦3

作者信息

  • 1. 北京大学口腔医学院·口腔医院牙周科,北京100081
  • 2. 北京高血压联盟研究所,北京100049
  • 3. 北京大学口腔医学院·口腔医院第二门诊部,北京100101
  • 折叠

摘要

Abstract

Objective: To survey the metabolic status of the middle-aged and aged population with periodontitis in Shijingshan community of Beijing, and investigate the relationship between periodontitis and metabolic syndrome (MS). Methods: The middle-aged and aged population in the community were investigated by questionnaires, periodontal clinical examinations and blood biochemical tests in 2005. A total of 903 subjects were enrolled, who were divided into two groups by severity of periodontitis. Their waist circumferences, values of high-density lipoprotein cholesterol ( HDL-C) , systolic blood pressure, fasting glucose, MS and its individual components (central obesity, insulin resistance, hypertriglyceri-demia, low HDL-C and hypertension) were compared between the two groups. The Logistic regression model was set to analyze the relationship between periodontitis and MS. Results: There was a significantly higher mean of systolic blood pressure, fasting glucose in the subjects with moderate-severe periodontitis than that with no-mild periodontitis. With severity of periodontitis increasing, the prevalence of MS, high blood glucose and low HDL-C increased significantly. After adjustment for gender, age, and smoking, the subjects with moderate-severe periodontitis were 1. 524, 1. 527 and 2. 349 times more likely to suffer from MS, high blood glucose and low HDL-C than those with no-mild periodontitis, respectively. Conclusion: With severity of periodontitis increasing, the prevalence of MS, high blood glucose and low HDL-C increased significantly in the middle-aged and aged population of the community in Beijing. Severity of periodontitis is associated with MS, high blood glucose and low HDL-C.

关键词

牙周炎/代谢综合征X/高血糖症/高密度脂蛋白胆固醇

Key words

Periodontitis/ Metabolic syndrome X/ Hyperglycemia/ Lipoproteins, HDL cholesterol

分类

医药卫生

引用本文复制引用

于卓人,刘丽笙,栾庆先,王兴宇,李蓬,沙月琴,刘曦..北京石景山区老年人群牙周炎与代谢综合征的相关性探讨[J].北京大学学报(医学版),2012,44(4):633-638,6.

基金项目

首都医学发展科研基金(2009-1019)资助 (2009-1019)

北京大学学报(医学版)

OA北大核心CSCDCSTPCD

1671-167X

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