北京大学学报(医学版)2012,Vol.44Issue(4):633-638,6.DOI:10.3969/j.issn.1671-167X.2012.04.031
北京石景山区老年人群牙周炎与代谢综合征的相关性探讨
Correlation between periodontitis and metabolic syndrome of the middle-aged and aged population in Shijingshan community of Beijing
摘要
Abstract
Objective: To survey the metabolic status of the middle-aged and aged population with periodontitis in Shijingshan community of Beijing, and investigate the relationship between periodontitis and metabolic syndrome (MS). Methods: The middle-aged and aged population in the community were investigated by questionnaires, periodontal clinical examinations and blood biochemical tests in 2005. A total of 903 subjects were enrolled, who were divided into two groups by severity of periodontitis. Their waist circumferences, values of high-density lipoprotein cholesterol ( HDL-C) , systolic blood pressure, fasting glucose, MS and its individual components (central obesity, insulin resistance, hypertriglyceri-demia, low HDL-C and hypertension) were compared between the two groups. The Logistic regression model was set to analyze the relationship between periodontitis and MS. Results: There was a significantly higher mean of systolic blood pressure, fasting glucose in the subjects with moderate-severe periodontitis than that with no-mild periodontitis. With severity of periodontitis increasing, the prevalence of MS, high blood glucose and low HDL-C increased significantly. After adjustment for gender, age, and smoking, the subjects with moderate-severe periodontitis were 1. 524, 1. 527 and 2. 349 times more likely to suffer from MS, high blood glucose and low HDL-C than those with no-mild periodontitis, respectively. Conclusion: With severity of periodontitis increasing, the prevalence of MS, high blood glucose and low HDL-C increased significantly in the middle-aged and aged population of the community in Beijing. Severity of periodontitis is associated with MS, high blood glucose and low HDL-C.关键词
牙周炎/代谢综合征X/高血糖症/高密度脂蛋白胆固醇Key words
Periodontitis/ Metabolic syndrome X/ Hyperglycemia/ Lipoproteins, HDL cholesterol分类
医药卫生引用本文复制引用
于卓人,刘丽笙,栾庆先,王兴宇,李蓬,沙月琴,刘曦..北京石景山区老年人群牙周炎与代谢综合征的相关性探讨[J].北京大学学报(医学版),2012,44(4):633-638,6.基金项目
首都医学发展科研基金(2009-1019)资助 (2009-1019)