摘要
Abstract
Objective: To analyze the relationship between early anti-coagulative therapy and acute coronary syndrome ( ACS) in the high-risk patients who have suffered percutaneous coronary intervention (PCI) recently during perioperative period of non-cardiac surgery. Methods: Patients who underwent scheduled non-cardiac surgery in our hospital from May 2009 to May 2011 were reviewed, of whom, 135 patients had suffered PCI therapy within 1 year, insisting on the treatment by taking aspirin and clopi-dogrel ( plaix) orally. These patients were administrated with heparin replacement treatment before scheduled surgeries. After surgeries, patients were divided into non-anticoagulative therapy group (63 cases) , low molecular weight heparin ( LMWH)-anticoagulative therapy group (36 cases) and unfrac-tionated heparin ( UFH)-anticoagulative therapy group (38 cases). The occurrence of ACS and hemorrhage in 3 days after operations was evaluated. Results: Of the 135 patients, 9 developed ACS in 3 days in non-anticoagulative therapy group and none in other 2 groups (P ＜0. 01 ). No statistical difference among the 3 groups in quantity of the blood transfusion was found. Conclusion: After scheduled non-cardiac surgeries, early and effective anticoagulative therapy administrated in the high-risk patients who have suffered PCI recently can obviously lower peri-operative incidence of acute coronary syndrome, and can be incapable of increasing risk of post-operative hemorrhage.关键词
血管成形术,经腔,经皮冠状动脉/抗凝药/围手术期/急性冠状动脉综合征Key words
Angioplasty, transluminal, percutaneous coronary/ Anticoagulants/ Perioperative period/ Acute coronary syndrome分类
医药卫生
