北京大学学报（医学版）2012，Vol.44Issue(5)：797-800,4.DOI:10.3969/j.issn.1671-167X.2012.05.026
骨诱导活性异种骨移植治疗牙周炎骨下袋的临床疗效评价
Clinical evaluation of periodontal intrabony defects treated with a reconstituted bovine porous bone mineral containing bone morphogenetic proteins
张立 1冯向辉 1路瑞芳 1孟焕新1
作者信息
- 1. 北京大学口腔医学院·口腔医院牙周科,北京100081
- 折叠
摘要
Abstract
Objective: To compare the outcomes of bovine porous bone mineral ( BPBM) containing bone morphogenetic proteins (BMP) and BPBM alone in periodontal intra-bony defects. Methods: In the study, 22 intrabony defects of 9 patients with periodontitis were recruited. All the patients had at least one pair of intrabony defects of ≥3 mm. The split-mouth and single blind methods were used. The defects were randomly assigned to BPBM containing BMP (test) or BPBM alone (control). After debride-ment, the intrabony defects were treated by bone graft. Assessments at baseline and after 6 months included plaque index, attachment level, probing pocket depth, bleeding indexes on probing and gingival recession. The early wound-healing, adverse effects and patients ' perceptions were also recorded. Results: The gain in clinical attachment was (3.0 ±1.2) mm in the test group and (3.2 + 1. 1) mm in the control group. The pocket reduction was (3. 4 ±1.5) mm in the test group and (2. 8 ±1.0) mm in the control group. The reduction of bleeding index was 1.9 ±1.3 in the test group and 2. 3 ±0. 8 in the control group. There was no statistical difference between the test group and control group ( P ＞ 0. 05 ). Conclusion: Both treatment modalities led to similar significant clinical improvements.关键词
牙周袋/骨形态发生蛋白质类/骨移植/骨代用品/治疗结果Key words
Periodontal pocket/ Bone morphogenetic proteins/ Bone transplantation/ Bone substitutes/ Treatment outcome分类
医药卫生引用本文复制引用
张立,冯向辉,路瑞芳,孟焕新..骨诱导活性异种骨移植治疗牙周炎骨下袋的临床疗效评价[J].北京大学学报（医学版）,2012,44(5):797-800,4.
