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MicroRNAs与多潜能干细胞的研究进展

王彩云 杨世华

动物学研究2012,Vol.33Issue(4):416-420,5.
动物学研究2012,Vol.33Issue(4):416-420,5.DOI:10.3724/SP.J.1141.2012.04416

MicroRNAs与多潜能干细胞的研究进展

Research on MicroRNAs in pluripotent stem cells

王彩云 1杨世华1

作者信息

  • 1. 昆明理工大学生命科学与技术学院,云南昆明650500
  • 折叠

摘要

Abstract

MicroRNAs (miRNAs) are a newly identified class of small regulatory non-coding endogenous RNAs that take part in a series of important processes by regulating gene expression. Recent studies have provided evidence that miRNAs may be involved in nearly all biological and metabolic processes, especially influencing self-renewal and differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). In this review, we briefly summarize the biological characteristics of miRNAs, the detection technologies, and the role of miRNAs regulation in ESCs and iPSCs to frame a discussion on the future prospects of miRNA research.

关键词

miRNAs/miRNAs检测/胚胎干细胞/诱导多能性干细胞

Key words

miRNAs/ miRNAs detection/ ESCs/ iPSCs

分类

生物科学

引用本文复制引用

王彩云,杨世华..MicroRNAs与多潜能干细胞的研究进展[J].动物学研究,2012,33(4):416-420,5.

基金项目

国家自然科学基金项目(31071279) (31071279)

云南省科技创新人才计划项目(2011CI009) (2011CI009)

动物学研究

OA北大核心CSCDCSTPCDMEDLINE

0254-5853

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