动物学研究2012,Vol.33Issue(4):416-420,5.DOI:10.3724/SP.J.1141.2012.04416
MicroRNAs与多潜能干细胞的研究进展
Research on MicroRNAs in pluripotent stem cells
摘要
Abstract
MicroRNAs (miRNAs) are a newly identified class of small regulatory non-coding endogenous RNAs that take part in a series of important processes by regulating gene expression. Recent studies have provided evidence that miRNAs may be involved in nearly all biological and metabolic processes, especially influencing self-renewal and differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). In this review, we briefly summarize the biological characteristics of miRNAs, the detection technologies, and the role of miRNAs regulation in ESCs and iPSCs to frame a discussion on the future prospects of miRNA research.关键词
miRNAs/miRNAs检测/胚胎干细胞/诱导多能性干细胞Key words
miRNAs/ miRNAs detection/ ESCs/ iPSCs分类
生物科学引用本文复制引用
王彩云,杨世华..MicroRNAs与多潜能干细胞的研究进展[J].动物学研究,2012,33(4):416-420,5.基金项目
国家自然科学基金项目(31071279) (31071279)
云南省科技创新人才计划项目(2011CI009) (2011CI009)