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108例儿童败血症临床特点及病原菌分析

侯瑶 殷峥

儿科药学杂志2012,Vol.18Issue(11):29-32,4.
儿科药学杂志2012,Vol.18Issue(11):29-32,4.

108例儿童败血症临床特点及病原菌分析

Analysis of Clinical Features and Etiologies in 108 Septic Children

侯瑶 1殷峥1

作者信息

  • 1. 昆明市儿童医院,云南昆明650034
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摘要

Abstract

Objective: To investigate clinical data, germiculture and drug sensitivity test of septic patients, as well as to understand clinical characteristics, etiology trend and antibiotic sensitivity of septic children in order to guide the rational use of antibiotics. Methods: To analyze retrospectively clinical data, hemoculture, antimicrobial susceptibility test of 108 septic children from August 2011 to February 2012. Results: Newborns were the majority in septic children in this investigation, accounting for 52.8%. The most common pathogens were Gram-positive bacilli, such as Staphylococcus epidermidis. The susceptibility to vancomycin for Gram-positive bacilli was as high as 100% in drug sensitivity test. Gram-positive bacilli was highly resistant to penicillin, erythromycin. Escherichia colin was the majority in Gram-negative bacilli. Gram-negative bacilli were sensitive to imipenem, meropenem, and cefoperazone/ sulbactam, which were resistant to piperacillin, cefazolin, ampicillin and cefuroxime. Conclusions: Newborns were the majority in septic children. Staphylococcus epidermidis was the major pathogen, which was highly sensitive to vancomycin. Pathogens reflected a certain degree of resistance to antibiotics.

关键词

败血症/病原菌/药物敏感试验

Key words

Sepsis/Pathogen/Drug sensitivity test

分类

医药卫生

引用本文复制引用

侯瑶,殷峥..108例儿童败血症临床特点及病原菌分析[J].儿科药学杂志,2012,18(11):29-32,4.

儿科药学杂志

OACSTPCD

1672-108X

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