国际医药卫生导报2012,Vol.18Issue(19):2833-2836,4.DOI:10.3760/cma.j.issn.1007-1245.2012.19.014
七氟醚与异氟醚用于婴幼儿唇腭裂修复术的麻醉效果比较
The anesthetic efficacy of sevoflurane versus that of isoflurane in surgical repair of cleft lips and cleft palates in infants and young children
张国强1
作者信息
- 1. 510623 广州市妇女儿童医疗中心儿童院区麻醉科
- 折叠
摘要
Abstract
Objective To compare the anesthetic efficacy of sevoflurane with that of isoflurane in surgical repair of cleft lips and cleft palates in infants and young children.Methods 100 ASA Ⅰ-Ⅱ infants and young children undergoing surgical repair were randomly assigned to receive sevoflurane ( 50 patients,sevoflurane group ) or isoflurane ( 50 patients,isoflurane group ) for maintaining general anesthesia.Time to awakening from medication termination,time to extubation,time to full consciousness,and incidence rate of complications were observed; Fa/Fi and levels of creatinine and urea nitrogen 24 h after surgery were noted.Results Time to awakening,time to extubation,and time to full consciousness was significantly shorter in sevoflurane group than in isoflurane group ( P< 0.05 ), the incidence rate of complications was significantly lower in sevoflurane group than in isoflurane group ( P< 0.05 ).Fa/Fi within 20 min was significantly greater in sevoflurane group than in isoflurane group ( P< 0.05 ) ; levels of creatinine and urea nitrogen did not differ significantly between these 2 groups 24 h after surgery ( P > 0.05 ).Conclusions Sevoflurane is safer and has a better anesthetic efficacy in surgical repair of cleft lips and cleft palates in infants and young children.关键词
唇裂/七氟醚/异氟醚/婴幼儿Key words
Cleft lips/Sevoflurane/Isoflurane/Infants and young children引用本文复制引用
张国强..七氟醚与异氟醚用于婴幼儿唇腭裂修复术的麻醉效果比较[J].国际医药卫生导报,2012,18(19):2833-2836,4.