国际妇产科学杂志2012，Vol.39Issue(4)：348-351,4.
肿瘤标记物在卵巢癌诊断中的研究进展
Advances on Tumor Markers for Diagnosis of Ovarian Cancer
摘要
Abstract
Ovarian cancer is one of the most common and lethal gynecological malignancy,leading cause of cancer deaths among women. It has been the main tumor that threatens the life and the health of women. The early clinical symptoms of ovarian cancer conceal,70% of the patients attending is late,the 5-year survival rate was only 30%,and 5 year's survival rate of early ovarian cancer was 90%. Now it is urgent and necessary to search new tumor markers with high specificity and sensitivity that are useful for early diagnosis of ovarian cancer and for the improvement of survival rate. Carbohydrate antigen,human epididymis 4(HE4),NECTIN4,lysophosphatidic acid(LPA),trkA and microRNA play a role in ovarian cancer diagnosis,of which CA125 is most widely used in clinical diagnosis. Micro RNAs as new tumor markers can improve the diagnosis methods of ovarian cancer.关键词
卵巢肿瘤/早期诊断/肿瘤标记,生物学/CA-125抗原/微RNAsKey words
Ovarian neoplasms/Early diagnosis/Tumor markers,biological/CA-125 antigen/MicroRNAs引用本文复制引用
陈立兰..肿瘤标记物在卵巢癌诊断中的研究进展[J].国际妇产科学杂志,2012,39(4):348-351,4.基金项目
上海市科学技术委员会科研计划项目(10dz2212100) （10dz2212100）
