中国妇幼健康研究2012，Vol.23Issue(5)：637-639,3.DOI:10.3969/j.issn.1673-5293.2012.05.029
影响上皮性卵巢癌复发的临床因素分析
Analysis of clinical factors influencing recurrence of epithelial ovarian cancer
王丽梅 1王红 2王树鹤 1刘晓艳3
作者信息
- 1. 北京军区总医院妇产科,北京,100700
- 2. 北京军区总医院超声科,北京,100700
- 3. 北京军区总医院病案质量管理科,北京,100700
- 折叠
摘要
Abstract
Objective To investigate the characteristics and related factors of recurrence of epithelial ovarian cancer ( EOC ) and seek for method of preventing and reducing recurrence. Methods The clinical data of 114 patients from July 2001 to June 2006 with EOC was retrospectively analyzed. Results The recurrence rate of EOC was 71. 1%( 81/114 )and the rate of recurrence at first two years was highest ( 71. 6% , 58/81 ). Pelvic cavity was the most common recurrence site, and the recurrence rate was 48. 1%( 39/81 ). The recurrence rate of stage I and II was lower than that of stage III and IV (X2 =21.0, P = 0.005 ), and that of well and moderately differentiated tissue was lower than that of poorly differentiated tissue (X2 =7.6,P = 0.009 ). Compared with that of cases >2 cm residue, the recurrence rate of cases≤2 cm residue was lower (X2 = 9. 5 ,P = 0. 005 ). The recurrence rate was 65. 3% in cases with more than 8 chemotherapy courses, and it was 82. 1% in those with less than 8 (X2 =4. 7 ,P =0.03 ). Meanwhile, the recurrence rate was related with the time when CA125 fell to normal level. The shorter the time, the lower the recurrence (X2 = 16. 6,P =0. 005 ). Conclusion The recurrence of EOC is highest within two years after operation, and the most common relapse and metastasis site is pelvic cavity. The recurrence is related with clinical stage, histological differentiation, regulating cytoreductive surgery, residual size and postoperative chemotherapy sensitivity.关键词
上皮性卵巢癌/复发/化疗/临床因素Key words
epithelial ovarian cancer ( EOC )/recurrence/chemotherapy/clinical factors分类
医药卫生引用本文复制引用
王丽梅,王红,王树鹤,刘晓艳..影响上皮性卵巢癌复发的临床因素分析[J].中国妇幼健康研究,2012,23(5):637-639,3.
