四川大学学报（医学版）2012，Vol.43Issue(5)：725-727,3.
肿瘤患者与健康对照人群半胱氨酸蛋白酶抑制剂C水平的比较研究
The Levels of Serum Cystatin C in Patients with Tumors and Healthy Controls
宋昊岚 1贺勇 1张宇 1王莉 2贾成瑶1
作者信息
- 1. 四川大学华西医院实验医学科临床生化室 成都610041
- 2. 四川大学华西医院中国循证医学中心 成都610041
- 折叠
摘要
Abstract
Objective To determine the association between serum cystatin C and tumors. Methods Serum samples were obtained from 273 patients with tumors and 185 healthy volunteers. Serum cystatin C was determined by particle-enhanced turbidimetric immuhoassay (PETIA). Student i-test, covariance analysis and multiple linear regressions were performed to examine the differences in the levels of cystatin C between the two groups. Results The student t-test did not show significant statistical differences in the serum cystatin C levels between the two groups (P = 0. 075). However, such differences became statistically significant (P<0. 01) after adjustment of age. The multiple liner regression demonstrated that healthy volunteers and men had higher levels of cystatin C than those with tumors and women. Cystatin C also increased with age and decreases with estimating glomerular filtration rate. Conclusion Cystatin C may be associated with the genesis and development of tumors.关键词
肿瘤/半胱氨酸蛋白酶抑制剂CKey words
Tumor/Cystatin C引用本文复制引用
宋昊岚,贺勇,张宇,王莉,贾成瑶..肿瘤患者与健康对照人群半胱氨酸蛋白酶抑制剂C水平的比较研究[J].四川大学学报（医学版）,2012,43(5):725-727,3.
