基础医学与临床2012，Vol.32Issue(10)：1179-1182,4.
去卵巢大鼠肾脏组织表达FSHR和LHR
The expression of FSHR and LHR in ovariectomized rat kidney
摘要
Abstract
Objective We discussed the similar features and changes in kidney and ovary. The aims of this study were to add new contents for the physiological functions of the kidney. Methods We prepared the model of ovariectomized rats, the characteristics of FSH Recepter( FSHR) , LH Recepter( LHR) in kidney were analyzed by ra-dioimmunoassay, RT-PCR semi-quantitative. Results In kidney and ovary, low dose of FSH and LH increased the level of the FSHR mRNA, LHR mRNA , while high dose of FSH and LH decreased the level of the FSHR mRNA, LHR mRNA; the high-dose estrogen significantly decreased the level of the FSHR mRNA from 0. 777 ± 0. 294 to 0. 514+0. 249(F <0. 05) . Conclusions In rat kidney and ovarian, the regulation characteristics of the FSHR, LHR were same, the kidney and ovarian may have similar functions.关键词
肾脏/内分泌/FSHR/LHRKey words
kidney/ endocrine/FSHR/ LHR分类
医药卫生引用本文复制引用
张哲,郑清莲,刘永惠..去卵巢大鼠肾脏组织表达FSHR和LHR[J].基础医学与临床,2012,32(10):1179-1182,4.基金项目
陕西中医管理局基金(2007-84) （2007-84）
