昆明医学院学报2012,Vol.33Issue(7):100-102,3.
艾司洛尔对全麻拔管期心血管反应的临床观察
Clinical Observation of Esmolol for Preventing the Cardiovascular Response to Tracheal Extubation
蔡瑛 1杨柳 1思永玉1
作者信息
- 1. 昆明医科大学第二附属医院麻醉科,云南昆明 650101
- 折叠
摘要
Abstract
Objective To observe the effect of esmolol on cardiovascular response to tracheal extubation. Methods Sixty patients with ASA I - II were randomly divided into two groups: control group (group A) and esmolol group (group B). Postoperative patients of general anesthesia were commanded to open eyes, then received normal saline (Group A) and esmolol 0.5 mg/kg (Group B) , respectively. HR, SpO2, SBP and DBP were monitored and recorded before induction (baseline) , before and after extubation, and 1, 2, 4, 10 min after extubation in all patients, and RPP were calculated. Results Compared with Group B, HR and RPP of patients in Group A increased significantly at extubating and in 4min after extubation (P< 0.05). There was no difference in SpO2, SBP and DBP between two groups (P > 0.05 ). Conclusion Esmolol is effective to attenuate the increase in HR and RPP, and can inhibit the cardiovascular response to tracheal extubation effectively and safely.关键词
艾司洛尔/拔管/心血管反应Key words
Esmolol/Tracheal extubation/Cardiovascular response分类
医药卫生引用本文复制引用
蔡瑛,杨柳,思永玉..艾司洛尔对全麻拔管期心血管反应的临床观察[J].昆明医学院学报,2012,33(7):100-102,3.